Massively parallel analysis of single-molecule dynamics on next-generation sequencing chips

J Aguirre Rivera, G Mao, A Sabantsev, M Panfilov… - Science, 2024 - science.org
Single-molecule techniques are ideally poised to characterize complex dynamics but are
typically limited to investigating a small number of different samples. However, a large …

Computational analysis on the dissemination of non-B DNA structural motifs in promoter regions of 1180 cellular genomes

VR Yella, A Vanaja - Biochimie, 2023 - Elsevier
The promoter regions of gene regulation are under evolutionary constraints and earlier
studies uncovered that they are characterized by enrichment of functional non-B DNA …

Unraveling the complexity: Advanced methods in analyzing DNA, RNA, and protein interactions

ML Peixoto, E Madan - Advances in cancer research, 2024 - pubmed.ncbi.nlm.nih.gov
Exploring the intricate interplay within and between nucleic acids, as well as their
interactions with proteins, holds pivotal significance in unraveling the molecular complexities …

Single-Molecule FRET: Principles and Analysis

B Israels, LM Lund, V Birkedal - Fluorescence Spectroscopy and …, 2023 - Springer
Förster resonance energy transfer (FRET) is a powerful spectroscopic technique to study
conformational changes of nucleic acids and proteins and their molecular interactions …