Examining horizontal gene transfer in microbial communities
IL Brito - Nature Reviews Microbiology, 2021 - nature.com
Bacteria acquire novel DNA through horizontal gene transfer (HGT), a process that enables
an organism to rapidly adapt to changing environmental conditions, provides a competitive …
an organism to rapidly adapt to changing environmental conditions, provides a competitive …
Piercing the dark matter: bioinformatics of long-range sequencing and mapping
Several new genomics technologies have become available that offer long-read sequencing
or long-range mapping with higher throughput and higher resolution analysis than ever …
or long-range mapping with higher throughput and higher resolution analysis than ever …
Generating lineage-resolved, complete metagenome-assembled genomes from complex microbial communities
Microbial communities might include distinct lineages of closely related organisms that
complicate metagenomic assembly and prevent the generation of complete metagenome …
complicate metagenomic assembly and prevent the generation of complete metagenome …
Assembly of 913 microbial genomes from metagenomic sequencing of the cow rumen
RD Stewart, MD Auffret, A Warr, AH Wiser… - Nature …, 2018 - nature.com
The cow rumen is adapted for the breakdown of plant material into energy and nutrients, a
task largely performed by enzymes encoded by the rumen microbiome. Here we present …
task largely performed by enzymes encoded by the rumen microbiome. Here we present …
Good microbes, bad genes? The dissemination of antimicrobial resistance in the human microbiome
A Crits-Christoph, HA Hallowell, K Koutouvalis… - Gut …, 2022 - Taylor & Francis
ABSTRACT A global rise in antimicrobial resistance among pathogenic bacteria has proved
to be a major public health threat, with the rate of multidrug-resistant bacterial infections …
to be a major public health threat, with the rate of multidrug-resistant bacterial infections …
Evaluating the information content of shallow shotgun metagenomics
Although microbial communities are associated with human, environmental, plant, and
animal health, there exists no cost-effective method for precisely characterizing species and …
animal health, there exists no cost-effective method for precisely characterizing species and …
Discovering multiple types of DNA methylation from bacteria and microbiome using nanopore sequencing
A Tourancheau, EA Mead, XS Zhang, G Fang - Nature methods, 2021 - nature.com
Bacterial DNA methylation occurs at diverse sequence contexts and plays important
functional roles in cellular defense and gene regulation. Existing methods for detecting DNA …
functional roles in cellular defense and gene regulation. Existing methods for detecting DNA …
Antimicrobial peptides: from design to clinical application
Infection of multidrug-resistant (MDR) bacteria, such as methicillin-resistant Staphylococcus
aureus (MRSA), carbapenem-resistant Enterobacteriaceae (CRE), and extended-spectrum …
aureus (MRSA), carbapenem-resistant Enterobacteriaceae (CRE), and extended-spectrum …
Genome-wide mapping and analysis of chromosome architecture
Chromosomes of eukaryotes adopt highly dynamic and complex hierarchical structures in
the nucleus. The three-dimensional (3D) organization of chromosomes profoundly affects …
the nucleus. The three-dimensional (3D) organization of chromosomes profoundly affects …
Computational approaches to predict bacteriophage–host relationships
Metagenomics has changed the face of virus discovery by enabling the accurate
identification of viral genome sequences without requiring isolation of the viruses. As a …
identification of viral genome sequences without requiring isolation of the viruses. As a …