• The specific situation of the patient. Unless otherwise provided for by national regulations,
off-label use of medication should be limited to situations where it is in the patient's interest …

BACKGROUND: The American Heart Association (AHA), in conjunction with the National
Institutes of Health, annually reports the most up-to-date statistics related to heart disease …

Document Reviewers: Luis Alcocer (Mexico), Christina Antza (Greece), Mustafa Arici
(Turkey), Eduardo Barbosa (Brazil), Adel Berbari (Lebanon), Luıs Bronze (Portugal), John …

Background: The American Heart Association, in conjunction with the National Institutes of
Health, annually reports the most up-to-date statistics related to heart disease, stroke, and …

Importance Hypertension, defined as persistent systolic blood pressure (SBP) at least 130
mm Hg or diastolic BP (DBP) at least 80 mm Hg, affects approximately 116 million adults in …

Background Salt substitutes with reduced sodium levels and increased potassium levels
have been shown to lower blood pressure, but their effects on cardiovascular and safety …

Background: The relationship between dietary sodium intake and blood pressure (BP) has
been tested in clinical trials and nonexperimental human studies, indicating a direct …

Hypertension is a major risk factor for cardiovascular and renal diseases in the United States
and worldwide. Obesity accounts for much of the risk for primary hypertension through …

Intake of salt is a biological imperative, inextricably woven into physiological systems,
human societies and global culture. However, excessive salt intake is associated with high …

Background Current evidence might support the use of omega‐3 fatty acids (preferably
docosahexaenoic acid and eicosapentaenoic acid) for lowering blood pressure (BP), but the …