Cells on chips
Microsystems create new opportunities for the spatial and temporal control of cell growth
and stimuli by combining surfaces that mimic complex biochemistries and geometries of the …
and stimuli by combining surfaces that mimic complex biochemistries and geometries of the …
Microfluidic devices for bioapplications
Harnessing the ability to precisely and reproducibly actuate fluids and manipulate
bioparticles such as DNA, cells, and molecules at the microscale, microfluidics is a powerful …
bioparticles such as DNA, cells, and molecules at the microscale, microfluidics is a powerful …
Integrating biosensors in organs-on-chip devices: A perspective on current strategies to monitor microphysiological systems
Organs-on-chip (OoC), often referred to as microphysiological systems (MPS), are advanced
in vitro tools able to replicate essential functions of human organs. Owing to their …
in vitro tools able to replicate essential functions of human organs. Owing to their …
3D in vitro modeling of the central nervous system
AM Hopkins, E DeSimone, K Chwalek… - Progress in …, 2015 - Elsevier
There are currently more than 600 diseases characterized as affecting the central nervous
system (CNS) which inflict neural damage. Unfortunately, few of these conditions have …
system (CNS) which inflict neural damage. Unfortunately, few of these conditions have …
Microfluidics for neuronal cell and circuit engineering
The widespread adoption of microfluidic devices among the neuroscience and neurobiology
communities has enabled addressing a broad range of questions at the molecular, cellular …
communities has enabled addressing a broad range of questions at the molecular, cellular …
Microfabricated mammalian organ systems and their integration into models of whole animals and humans
While in vitro cell based systems have been an invaluable tool in biology, they often suffer
from a lack of physiological relevance. The discrepancy between the in vitro and in vivo …
from a lack of physiological relevance. The discrepancy between the in vitro and in vivo …
Digital microfluidics for cell-based assays
I Barbulovic-Nad, H Yang, PS Park, AR Wheeler - Lab on a Chip, 2008 - pubs.rsc.org
We introduce a new method for implementing cell-based assays. The method is based on
digital microfluidics (DMF) which is used to actuate nanolitre droplets of reagents and cells …
digital microfluidics (DMF) which is used to actuate nanolitre droplets of reagents and cells …
Will microfluidics enable functionally integrated biohybrid robots?
The next robotics frontier will be led by biohybrids. Capable biohybrid robots require
microfluidics to sustain, improve, and scale the architectural complexity of their core …
microfluidics to sustain, improve, and scale the architectural complexity of their core …
Functional characterization of human pluripotent stem cell-derived models of the brain with microelectrode arrays
A Pelkonen, C Pistono, P Klecki, M Gómez-Budia… - Cells, 2021 - mdpi.com
Human pluripotent stem cell (hPSC)-derived neuron cultures have emerged as models of
electrical activity in the human brain. Microelectrode arrays (MEAs) measure changes in the …
electrical activity in the human brain. Microelectrode arrays (MEAs) measure changes in the …
Microfluidic compartmentalized co-culture platform for CNS axon myelination research
This paper presents a circular microfluidic compartmentalized co-culture platform that can be
used for central nervous system (CNS) axon myelination research. The microfluidic platform …
used for central nervous system (CNS) axon myelination research. The microfluidic platform …