Borrelia burgdorferi is the causative agent of Lyme disease and is transmitted to vertebrate
hosts by Ixodes spp. ticks. The spirochaete relies heavily on its arthropod host for basic …

The spirochete Borrelia burgdorferi is a tick-borne obligate parasite whose normal reservoir
is a variety of small mammals. Although infection of these natural hosts does not lead to …

RpoS and RpoN are two alternative sigma factors typically associated with general stress
responses in bacteria. To date, there has been no experimental evidence that RpoS and …

Borrelia burgdorferi is the etiologic agent of Lyme disease, the most prevalent arthropod-
borne disease in the United States. The genome of the type strain, B31, consists of a …

DNA microarrays were used to survey the adaptive genetic responses of Borrelia burgdorferi
(Bb) B31, the Lyme disease spirochete, when grown under conditions analogous to those …

Spirochete motility is enigmatic: It differs from the motility of most other bacteria in that the
entire bacterium is involved in translocation in the absence of external appendages. Using …

Borrelia burgdorferi, the spirochete that causes Lyme disease, is maintained in nature via an
enzootic cycle that comprises a tick vector and a vertebrate host. Transmission from the tick …

Borrelia burgdorferi (Bb) adapts to its arthropod and mammalian hosts by altering its
transcriptional and antigenic profiles in response to environmental signals associated with …

Borrelia burgdorferi, a spirochaete that causes Lyme borreliosis, contains 21 linear and
circular plasmids thought to be important for survival in mammals or ticks. Our results …

Lyme disease is the most commonly reported vector-borne disease in North America and
Europe, yet we know little about which components of the causative agent, Borrelia …