PrankWeb 3: accelerated ligand-binding site predictions for experimental and modelled protein structures
Abstract Knowledge of protein–ligand binding sites (LBSs) enables research ranging from
protein function annotation to structure-based drug design. To this end, we have previously …
protein function annotation to structure-based drug design. To this end, we have previously …
NDP52 acts as a redox sensor in PINK1/Parkin‐mediated mitophagy
Mitophagy, the elimination of mitochondria via the autophagy‐lysosome pathway, is
essential for the maintenance of cellular homeostasis. The best characterised mitophagy …
essential for the maintenance of cellular homeostasis. The best characterised mitophagy …
[HTML][HTML] Analysis of critical protein–protein interactions of SARS-CoV-2 capping and proofreading molecular machineries towards designing dual target inhibitory …
F Arabi-Jeshvaghani, F Javadi‐Zarnaghi… - Scientific Reports, 2023 - nature.com
In recent years, the emergence of severe acute respiratory syndrome coronavirus 2 (SARS-
CoV-2), as the cause of the coronavirus disease (COVID-19) global pandemic, and its …
CoV-2), as the cause of the coronavirus disease (COVID-19) global pandemic, and its …
Deciphering a crucial dimeric interface governing Norrin dimerization and the pathogenesis of familial exudative vitreoretinopathy
R Zhao, M Liu, E Dai, C Chen, L Lv, L Peng… - The FASEB …, 2024 - Wiley Online Library
Familial exudative vitreoretinopathy (FEVR) is a hereditary eye disease that could cause
blindness. It has been established that Norrin forms dimers to activate β‐catenin signaling …
blindness. It has been established that Norrin forms dimers to activate β‐catenin signaling …
Computational identification of key residues regulating fluorescence emission in a red/green cyanobacteriochrome
P Kannan, J Oh, YJ Yeon, YI Park… - Proteins: Structure …, 2024 - Wiley Online Library
Cyanobacteriochromes (CBCRs) are linear tetrapyrrole bilin‐binding photoreceptors of
cyanobacteria that exhibit high spectral diversity, gaining attention in optogenetics and …
cyanobacteria that exhibit high spectral diversity, gaining attention in optogenetics and …