Abstract Glutathione peroxidase 4 (GPx4) moonlights as structural protein and antioxidase
that powerfully inhibits lipid oxidation. In the past years, it is considered as a key regulator of …

ATF4 is a cellular stress induced bZIP transcription factor that is a hallmark effector of the
integrated stress response. The integrated stress response is triggered by phosphorylation …

Redox homeostasis refers to the balance between the production of reactive oxygen species
(ROS) as well as reactive nitrogen species (RNS), and their elimination by antioxidants. It is …

Combining existing drug therapy is essential in developing new therapeutic agents in
disease prevention and treatment. In preclinical investigations, combined effect of certain …

The aggregation of amyloid-beta peptide and tau protein dysregulation are implicated to
play key roles in Alzheimer's disease pathogenesis and are considered the main …

Chronological aging is by far the strongest risk factor for age-related dementia and
Alzheimer's disease. Senescent cells accumulated in the aging and Alzheimer's disease …

Alzheimer's disease (AD) is a progressive neurodegenerative disease, and it is currently the
seventh leading cause of death worldwide. It is characterized by the extracellular …

Boswellia serrata gum is a natural product that showed beneficial effects on
neurodegenerative diseases in recent studies. In this study, we investigated the effects of …

Alzheimer's disease (AD) is the most common form of dementia. AD is a progressive
neurodegenerative disorder characterized by cognitive dysfunction, including learning and …

A mobile phone is now a commonly used device for digital media and communication
among all age groups. Young adolescents use it for longer durations, which exposes them …