Precision nutrition: a review of personalized nutritional approaches for the prevention and management of metabolic syndrome

J de Toro-Martín, BJ Arsenault, JP Després, MC Vohl - Nutrients, 2017 - mdpi.com
The translation of the growing increase of findings emerging from basic nutritional science
into meaningful and clinically relevant dietary advices represents nowadays one of the main …

The contribution of genetics and environment to obesity

D Albuquerque, C Nóbrega, L Manco… - British medical …, 2017 - academic.oup.com
Background Obesity is a global health problem mainly attributed to lifestyle changes such as
diet, low physical activity or socioeconomics factors. However, several evidences …

FTO genotype and weight loss: systematic review and meta-analysis of 9563 individual participant data from eight randomised controlled trials

KM Livingstone, C Celis-Morales, GD Papandonatos… - bmj, 2016 - bmj.com
Objective To assess the effect of the FTO genotype on weight loss after dietary, physical
activity, or drug based interventions in randomised controlled trials. Design Systematic …

Nutrigenomics in the modern era

JC Mathers - Proceedings of the Nutrition Society, 2017 - cambridge.org
The concept that interactions between nutrition and genetics determine phenotype was
established by Garrod at the beginning of the 20th century through his ground-breaking …

[HTML][HTML] Complex relationship between obesity and the fat mass and obesity locus

Q Yang, T Xiao, J Guo, Z Su - International journal of biological …, 2017 - ncbi.nlm.nih.gov
In the 21st century, obesity has become a serious problem because of increasing obese
patients and numerous metabolic complications. The primary reasons for this situation are …

[HTML][HTML] Can genetic-based advice help you lose weight? Findings from the Food4Me European randomized controlled trial

C Celis-Morales, CFM Marsaux, KM Livingstone… - The American journal of …, 2017 - Elsevier
Background: There has been limited evidence about whether genotype-tailored advice
provides extra benefits in reducing obesity-related traits compared with the benefits of …

Personalized nutrition intervention improves health status in overweight/obese chinese adults: a randomized controlled trial

J Kan, J Ni, K Xue, F Wang, J Zheng, J Cheng… - Frontiers in …, 2022 - frontiersin.org
Background Overweight and obesity increase the risk of noncommunicable diseases
(NCDs). Personalized nutrition (PN) approaches may provide tailored nutritional …

Appraisal of gene-environment interactions in GWAS for evidence-based precision nutrition implementation

R San-Cristobal, J de Toro-Martín, MC Vohl - Current Nutrition Reports, 2022 - Springer
Abstract Purpose of Review This review aims to analyse the currently reported gene-
environment (G× E) interactions in genome-wide association studies (GWAS), involving …

Obesity genetics and cardiometabolic health: Potential for risk prediction

DK Sanghera, C Bejar, S Sharma… - Diabetes, Obesity …, 2019 - Wiley Online Library
The increasing burden of obesity worldwide and its effect on cardiovascular disease (CVD)
risk is an opportunity for evaluation of preventive approaches. Both obesity and CVD have a …

Dietary fat and total energy intake modifies the association of genetic profile risk score on obesity: evidence from 48 170 UK Biobank participants

CA Celis-Morales, DM Lyall, SR Gray, L Steell… - International journal of …, 2017 - nature.com
Background: Obesity is a multifactorial condition influenced by both genetics and lifestyle.
The aim of this study was to investigate whether the association between a validated genetic …