The implication of the gut microbiome in heart failure

VV Lupu, A Adam Raileanu, CM Mihai, ID Morariu… - Cells, 2023 - mdpi.com
Heart failure is a worldwide health problem with important consequences for the overall
wellbeing of affected individuals as well as for the healthcare system. Over recent decades …

NSAID–gut microbiota interactions

D Maseda, E Ricciotti - Frontiers in pharmacology, 2020 - frontiersin.org
Nonsteroidal anti-inflammatory drugs (NSAID) s relieve pain, inflammation, and fever by
inhibiting the activity of cyclooxygenase isozymes (COX-1 and COX-2). Despite their clinical …

Current knowledge on non-steroidal anti-inflammatory drug-induced small-bowel damage: a comprehensive review

T Watanabe, Y Fujiwara, FKL Chan - Journal of gastroenterology, 2020 - Springer
Recent advances in small-bowel endoscopy such as capsule endoscopy have shown that
non-steroidal anti-inflammatory drugs (NSAIDs) frequently damage the small intestine, with …

Soluble fibre supplementation with and without a probiotic in adults with asthma: A 7-day randomised, double blind, three way cross-over trial

R McLoughlin, BS Berthon, GB Rogers, KJ Baines… - …, 2019 - thelancet.com
Background Soluble fibre modulates airway inflammation in animal models. The aim of this
study was to investigate the effects of soluble fibre supplementation, with and without a …

Bifidobacterium dentium-derived y-glutamylcysteine suppresses ER-mediated goblet cell stress and reduces TNBS-driven colonic inflammation

MA Engevik, B Herrmann, W Ruan, AC Engevik… - Gut …, 2021 - Taylor & Francis
Endoplasmic reticulum (ER) stress compromises the secretion of MUC2 from goblet cells
and has been linked with inflammatory bowel disease (IBD). Although Bifidobacterium can …

Pharmacogenomics of NSAID-induced upper gastrointestinal toxicity

L McEvoy, DF Carr, M Pirmohamed - Frontiers in pharmacology, 2021 - frontiersin.org
Non-steroidal anti-inflammatory drugs (NSAIDs) are a group of drugs which are widely used
globally for the treatment of pain and inflammation, and in the case of aspirin, for secondary …

Gut microbiota in NSAID enteropathy: new insights from inside

X Wang, Q Tang, H Hou, W Zhang, M Li… - Frontiers in cellular …, 2021 - frontiersin.org
As a class of the commonly used drugs in clinical practice, non-steroidal anti-inflammatory
drugs (NSAIDs) can cause a series of adverse events including gastrointestinal injuries …

Contribution of the gut microbiome to drug disposition, pharmacokinetic and pharmacodynamic variability

SM Tsunoda, C Gonzales, AK Jarmusch… - Clinical …, 2021 - Springer
The trillions of microbes that make up the gut microbiome are an important contributor to
health and disease. With respect to xenobiotics, particularly orally administered compounds …

The role of probiotics in children with autism spectrum disorders: A study protocol for a randomised controlled trial

L Zhang, Y Xu, H Li, B Li, G Duan, C Zhu - PLoS One, 2022 - journals.plos.org
Background Autism spectrum disorder (ASD) is a neurological and developmental condition
that begins in infancy or earlier and lasts through the individual's lifetime. The aetiology and …

Gastrointestinal disorders and intestinal bacteria: advances in research and applications in therapy

T Ohkusa, Y Nishikawa, N Sato - Frontiers in Medicine, 2023 - frontiersin.org
Intestinal bacteria coexist with humans and play a role in suppressing the invasion of
pathogens, producing short-chain fatty acids, producing vitamins, and controlling the …