Systematic review of the pharmacological agents that have been tested against spreading depolarizations

A Klass, R Sánchez-Porras… - Journal of Cerebral Blood …, 2018 - journals.sagepub.com
Spreading depolarization (SD) occurs alongside brain injuries and it can lead to neuronal
damage. Therefore, pharmacological modulation of SD can constitute a therapeutic …

Dysfunctional microRNA-144-3p/ZBTB20/ERK/CREB1 signalling pathway is associated with MK-801-induced schizophrenia-like abnormalities

B Pan, B Han, X Zhu, Y Wang, H Ji, J Weng, Y Liu - Brain Research, 2023 - Elsevier
Schizophrenia is a group of severe mental disorders. ZBTB20 is critical in brain
development and corticogenesis and its dysfunction induces various neural disorders …

[PDF][PDF] Propionic acid and not caproic acid, attenuates nonalcoholic steatohepatitis and improves (cerebro) vascular functions in obese Ldlr (-/-). Leiden mice

AC Tengeler, E Gart, M Wiesmann, IAC Arnoldussen… - 2020 - repository.ubn.ru.nl
The obesity epidemic increases the interest to elucidate impact of short-chain fatty acids on
metabolism, obesity, and the brain. We investigated the effects of propionic acid (PA) and …

Effects of icariin on alleviating schizophrenia-like symptoms by regulating the miR-144-3p/ATP1B2/mTOR signalling pathway

B Pan, L Xu, J Weng, Y Wang, H Ji, B Han, X Zhu… - Neuroscience …, 2022 - Elsevier
Schizophrenia is a group of severe mental disorders. Icariin is a main active component of
Epimedium, possessing therapeutic effects on various neurodegenerative diseases. The …

EPO Deficiency Upregulates GADD45b/p38 MAPK Axis, Mediating Schizophrenia‐Related Synaptic and Cognitive Impairments

C Guo, W Li, Y Liu, X Tao, YAR Mahaman… - Advanced …, 2024 - Wiley Online Library
Schizophrenia (SZ) is a chronic and severe mental illness associated with psychiatric
symptoms, cognitive deficits, and social dysfunction. Current clinical interventions only limit …

Altered expression levels of miR-144-3p and ATP1B2 are associated with schizophrenia

B Pan, Y Wang, Y Shi, Q Yang, B Han… - The World Journal of …, 2022 - Taylor & Francis
Objectives: Schizophrenia is a devastating mental disease. Various microRNAs were proven
to be associated with schizophrenia. Altered microRNA-144-3p (miR-144-3p) levels were …

[HTML][HTML] Reduced d-serine levels drive enhanced non-ionotropic NMDA receptor signaling and destabilization of dendritic spines in a mouse model for studying …

DK Park, S Petshow, M Anisimova, EV Barragan… - Neurobiology of …, 2022 - Elsevier
Schizophrenia is a psychiatric disorder that affects over 20 million people globally. Notably,
schizophrenia is associated with decreased density of dendritic spines and decreased …

NT3 treatment alters spinal cord injury-induced changes in the gray matter volume of rhesus monkey cortex

SS Bao, C Zhao, HW Chen, T Feng, XJ Guo, M Xu… - Scientific Reports, 2022 - nature.com
Spinal cord injury (SCI) may cause structural alterations in brain due to pathophysiological
processes, but the effects of SCI treatment on brain have rarely been reported. Here, voxel …

Aberrant temporal behavior of mismatch negativity generators in schizophrenia patients and subjects at clinical high risk for psychosis

M Kim, KIK Cho, YB Yoon, TY Lee, JS Kwon - Clinical Neurophysiology, 2017 - Elsevier
Objective Although disconnection syndrome has been considered a core pathophysiologic
mechanism of schizophrenia, little is known about the temporal behavior of mismatch …

Repeated exposure to high-dose nicotine induces prefrontal gray matter atrophy in adolescent male rats

X Chen, K Long, S Liu, Y Cai, L Cheng, W Chen, F Lin… - Neuroscience, 2024 - Elsevier
Incidences of seizure after e-cigarette use in adolescents and young adults have been
reported, raising the concern about the risk of nicotine overconsumption. Few previous …