Redox biology is at the core of life sciences, accompanied by the close correlation of redox
processes with biological activities. Redox homeostasis is a prerequisite for human health …

Central nervous system (CNS) disorders and diseases are expected to rise sharply in the
coming years, partly because of the world's aging population. Medicines for the treatment of …

Memory impairment occurs in over a third of patients after symptomatic stroke. Memory
deficits rarely occur in isolation but are an important component of the poststroke cognitive …

Magnetic resonance imaging (MRI) and positron emission tomography (PET) have made
great strides in the diagnosis and our understanding of Alzheimer's Disease (AD). Despite …

Introduction Certain genes increase the risk of age-related neurological dysfunction and/or
disease. For instance, ApoE is a well-known gene carrying risk for Alzheimer's disease …

Alzheimer's disease (AD) is a prevalent type of dementia in elderly populations with a
significant genetic component. The accumulating evidence suggests that AD involves a …

INTRODUCTION We sought to characterize the timing of changes in cognitive trajectories
related to genetic risk using the apolipoprotein E (APOE) score, a continuous measure of …

The association of calcium signaling pathway gene variants, bone mineral density (BMD)
and mild cognitive impairment (MCI) is poorly understood so far. A total of 878 participants …

Background: Given the established genetic linkage between triggering receptors expressed
on myeloid cells 2 (TREM2) and Alzheimer's disease (AD), an expanding research body has …

With people living longer, the societal impact of age-related cognitive decline is becoming
more pronounced (Crimmins, 2015). Thus, it is increasingly important to comprehend the …