Targeted drug delivery using nanobodies to deliver effective molecules to breast cancer cells: the most attractive application of nanobodies

MH Abdolvahab, P Karimi, N Mohajeri, M Abedini… - Cancer Cell …, 2024 - Springer
Targeted drug delivery is one of the attractive ways in which cancer treatment can
significantly reduce side effects. In the last two decades, the use of antibodies as a tool for …

A Nanorobotics-Based Approach of Breast Cancer in the Nanotechnology Era

AN Neagu, T Jayaweera, K Weraduwage… - International Journal of …, 2024 - mdpi.com
We are living in an era of advanced nanoscience and nanotechnology. Numerous
nanomaterials, culminating in nanorobots, have demonstrated ingenious applications in …

Development of anti-membrane type 1-matrix metalloproteinase nanobodies as immunoPET probes for triple negative breast cancer imaging

F Mulero, M Oteo, G Garaulet, N Magro… - Frontiers in …, 2022 - frontiersin.org
Triple-negative breast cancer (TNBC) is characterized by aggressiveness and high rates of
metastasis. The identification of relevant biomarkers is crucial to improve outcomes for …

Inhibitory Impact Of Cinobufagin In Triple-Negative Breast Cancer Metastasis: Involvements Of Macrophage Reprogramming Through Upregulated MME and …

Z Zhu, H Wang, X Qian, M Xue, A Sun, Y Yin, J Tang… - Clinical breast …, 2024 - Elsevier
Background Cinobufagin (CBG), a key bioactive component in cinobufacini, exhibits
antitumor properties. This study explores CBG's impact on triple-negative breast cancer …

Nanobodies for the early detection of ovarian cancer

LH Tran, GJ Graulus, C Vincke, N Smiejkowska… - International journal of …, 2022 - mdpi.com
Ovarian cancer ranks fifth in cancer-related deaths among women. Since ovarian cancer
patients are often asymptomatic, most patients are diagnosed only at an advanced stage of …

Development of a bioluminescent homogenous nanobody-based immunoassay for the detection of prostate-specific antigen (PSA)

ME Baghdadi, R Emamzadeh, M Nazari… - Enzyme and Microbial …, 2024 - Elsevier
Prostate cancer is the most prevalent cancer in men. At present, the diagnosis and
screening of prostate cancer rely on the essential biomarker known as prostate-specific …

[HTML][HTML] Bibliometric analysis of phosphoglycerate kinase 1 expression in breast cancer and its distinct upregulation in triple-negative breast cancer

JY Chen, JD Li, RQ He, ZG Huang… - World Journal of …, 2024 - ncbi.nlm.nih.gov
BACKGROUND Phosphoglycerate kinase 1 (PGK1) has been identified as a possible
biomarker for breast cancer (BC) and may play a role in the development and advancement …

Nanobody engineering: computational modelling and design for biomedical and therapeutic applications

NS El Salamouni, JH Cater, LM Spenkelink… - FEBS Open Bio, 2024 - Wiley Online Library
Nanobodies, the smallest functional antibody fragment derived from camelid heavy‐chain‐
only antibodies, have emerged as powerful tools for diverse biomedical applications. In this …

Carbonic Anhydrase IX Enzyme in Triple Negative Breast Carcinoma: Relationship with prognostic factors and response to neoadjuvant chemotherapy

ÖA Solmaz, N Kutluer, MB Bozan - 2024 - researchsquare.com
Purpose Triple negative breast carcinoma is characterized by the absence of estrogen
receptor, progesterone receptor and HER2/neu receptor. Carbonic anhydrase IX (CA IX) is a …