Background: Physical exercise may be valuable for patients with schizophrenia spectrum
disorders as it may have beneficial effect on clinical symptoms, quality of life and cognition …

Motivation deficits, such as apathy, are pervasive in both neurological and psychiatric
diseases. Even when they are not the core symptom, they reduce quality of life, compromise …

Negative symptoms have long been conceptualized as a core aspect of schizophrenia. They
play a key role in the functional outcome of the disorder, and their management represents a …

Objective: The authors examined the safety and efficacy of antidepressants added to
antipsychotic drugs in the treatment of schizophrenia. Method: Multiple databases and …

Objective Antipsychotic effects of immunomodulating drugs have been suggested; however,
a thorough, comprehensive meta-analysis on the effect and safety of anti-inflammatory add …

Since currently available antipsychotic medications predominantly treat hallucinations,
delusions, disorganized thoughts and behavior, and related agitation/aggression, attention …

Negative symptoms, in particular motivational deficits, are reported as impediments to
functional recovery in patients with schizophrenia. This study examined the prevalence of …

The first psychotic episode is classically viewed as a critical period which management is
important in determining the long-term outcome of the schizophrenia (SCZ). For this reason …

Background: Negative symptoms in schizophrenia are heterogeneous and
multidimensional; effective treatments are lacking. Cariprazine, a dopamine D3-preferring …

Background: Negative symptoms are frequent in patients with schizophrenia and are
associated with marked impairments in social functioning. The efficacy of drug-based …