Multidrug-resistant tuberculosis: latest opinions on epidemiology, rapid diagnosis and management

PS Nyasulu, CO Doumbia, V Ngah… - Current Opinion in …, 2024 - journals.lww.com
To effectively manage MDR-TB and its co-morbidity with HIV/AIDS, proactive screening
programs are imperative. The review highlights the necessity of active follow-up strategies to …

Genotypic and phenotypic comparison of drug resistance profiles of clinical multidrug-resistant Mycobacterium tuberculosis isolates using whole genome sequencing …

A Vīksna, D Sadovska, I Berge, I Bogdanova… - BMC Infectious …, 2023 - Springer
Background Multidrug-resistant tuberculosis (MDR–TB) remains a major public health
problem in many high tuberculosis (TB) burden countries. Phenotypic drug susceptibility …

Bedaquiline Resistance and Molecular Characterization of Rifampicin-Resistant Mycobacterium Tuberculosis Isolates in Zhejiang, China

E Tong, Y Zhou, Z Liu, Y Zhu, M Zhang… - Infection and Drug …, 2023 - Taylor & Francis
Purpose This study aimed to determine the prevalence and molecular characterization of
bedaquiline (BDQ) resistance among rifampicin-resistant tuberculosis (RR-TB) isolates …

Molecular mechanisms of resistance and treatment efficacy of clofazimine and bedaquiline against Mycobacterium tuberculosis

MM Islam, MS Alam, Z Liu, MS Khatun, B Yusuf… - Frontiers in …, 2024 - frontiersin.org
Clofazimine (CFZ) and bedaquiline (BDQ) are currently used for the treatment of multidrug-
resistant (MDR) Mycobacterium tuberculosis (Mtb) strains. In recent years, adding CFZ and …

HIV co-infection is associated with reduced Mycobacterium tuberculosis transmissibility in sub-Saharan Africa

EM Windels, EM Wampande, ML Joloba… - PLoS …, 2024 - journals.plos.org
Persons living with HIV are known to be at increased risk of developing tuberculosis (TB)
disease upon infection with Mycobacterium tuberculosis (Mtb). However, it has remained …

Genomic, phenotypic and demographic characterization of Mycobacterium tuberculosis in Israel in 2021

Y Losev, M Rubinstein, I Nissan, P Haviv… - Frontiers in Cellular …, 2023 - frontiersin.org
According to World Health Organization WHO, Tuberculosis (TB) is the second cause of
death from infectious disease worldwide. During 2021, 10.6 million people were infected …

Mycobacterium tuberculosis Lineage Distribution Using Whole‐Genome Sequencing and Bedaquiline, Clofazimine, and Linezolid Phenotypic Profiles among …

A Rukmana, C Gozali, L Erlina - International Journal of …, 2024 - Wiley Online Library
Tuberculosis (TB) is caused by Mycobacterium tuberculosis infection. Indonesia is ranked
second in the world for TB cases. New anti‐TB drugs from groups A and B, such as …

[HTML][HTML] African Centers of Excellence in Bioinformatics and Data Intensive Science: Building Capacity for Enhancing Data Intensive Infectious Diseases Research in …

MY Giovanni, C Whalen, DE Hurt… - Journal of infectious …, 2023 - ncbi.nlm.nih.gov
Africa faces both a disproportionate burden of infectious diseases coupled with unmet needs
in bioinformatics and data science capabilities which impacts the ability of African …

[HTML][HTML] Acquired bedaquiline and fluoroquinolones resistance during treatment follow-up in Oromia Region, North Shewa, Ethiopia

G Diriba, A Alemu, BZ Ayano, B Yenew, M Hailu… - IDCases, 2024 - Elsevier
Background Bedaquiline (BDQ) is an effective drug currently used for multidrug-resistant or
rifampicin-resistant TB (MDR/RR-TB) and pre-extensively drug-resistant TB (pre-XDR-TB) …

Генетические аспекты лекарственной устойчивости микобактерий туберкулеза к новым препаратам с противотуберкулезной активностью

АВ Кукурика, ЕИ Веселова… - Туберкулез и болезни …, 2023 - tibl-journal.com
Аннотация Проанализированы 57 публикаций, посвященных изучению генетических
механизмов формирования лекарственной устойчивости микобактерий туберкулеза к …