The antifungal action mode of the rice endophyte Streptomyces hygroscopicus OsiSh-2 as a potential biocontrol agent against the rice blast pathogen

T Xu, L Cao, J Zeng, CMM Franco, Y Yang, X Hu… - Pesticide biochemistry …, 2019 - Elsevier
Microbial antagonists and their bioactive metabolites provide one of the best alternatives to
chemical pesticides to control crop disease for sustainable agriculture and global food …

Alternative treatment of fungal infections: Synergy with non‐antifungal agents

L Rossato, M Camargo dos Santos, RG Vitale… - Mycoses, 2021 - Wiley Online Library
Fungal infections are responsible for high mortality rates in immunocompromised and high‐
risk surgical patients. Therapy failures during the last decades due to increasing multidrug …

[HTML][HTML] Novel Anti-Neuroinflammatory Properties of a Thiosemicarbazone–Pyridylhydrazone Copper (II) Complex

XY Choo, LE McInnes, A Grubman… - International Journal of …, 2022 - mdpi.com
Neuroinflammation has a major role in several brain disorders including Alzheimer's
disease (AD), yet at present there are no effective anti-neuroinflammatory therapeutics …

Discovery of carboline derivatives as potent antifungal agents for the treatment of cryptococcal meningitis

J Tu, Z Li, Y Jiang, C Ji, G Han, Y Wang… - Journal of Medicinal …, 2019 - ACS Publications
Clinical treatment of cryptococcal meningitis (CM) remains a significant challenge because
of the lack of effective and safe drug therapies. Developing novel CM therapeutic agents …

Epitope‐Based Immunoinformatic Approach on Heat Shock 70 kDa Protein Complex of Cryptococcus neoformans var. grubii

RM Elhassan, NM Alsony, KM Othman… - Journal of …, 2021 - Wiley Online Library
Introduction. Cryptococcosis is a ubiquitous opportunistic fungal disease caused by
Cryptococcus neoformans var. grubii. It has high global morbidity and mortality among HIV …

Discovery of novel simplified isoxazole derivatives of sampangine as potent anti-cryptococcal agents

Z Li, N Liu, J Tu, C Ji, G Han, Y Wang… - Bioorganic & Medicinal …, 2019 - Elsevier
Cryptococcus neoformans is the leading cause of cryptococcal meningitis, which is
associated with high mortality due to lack of effective treatment. Herein a series of tricyclic …

A copper(II)-binding triazole derivative with ionophore properties is active against Candida spp.

A Gaspar-Cordeiro, S da Silva, M Aguiar… - JBIC Journal of …, 2020 - Springer
Invasive fungal infections (IFIs) are life threatening and existing antifungal drugs are not
completely effective due to undesirable side effects and resistance emergence. Azoles are …