Hypoxia is known to be a poor prognostic indicator for nearly all solid tumours and also is
predictive of treatment failure for radiotherapy, chemotherapy, surgery and targeted …

In animal models of cancer, oncologic imaging has evolved from a simple assessment of
tumor location and size to sophisticated multimodality exploration of molecular, physiologic …

There is a clinical need for noninvasive biomarkers of tumor hypoxia for prognostic and
predictive studies, radiotherapy planning, and therapy monitoring. Oxygen-enhanced MRI …

Abstract Oxygen-Enhanced Magnetic Resonance Imaging (OE-MRI) techniques were
evaluated as potential non-invasive predictive biomarkers of radiation response. Semi …

Purpose Distinguishing radiation necrosis (RN) from recurrent tumor remains a vexing
clinical problem with important health-care consequences for neuro-oncology patients …

The complexity of modern in vivo magnetic resonance imaging (MRI) methods in oncology
has dramatically changed in the last 10 years. The field has long since moved passed its …

Purpose To develop a noninvasive prognostic imaging biomarker related to hypoxia to
predict SABR tumor control. Methods and Materials A total of 145 subcutaneous syngeneic …

Purpose: Glioblastoma multiforme (GBM) is a hypoxic tumor resistant to radiotherapy. The
purpose of this study was to assess the safety and efficacy of a novel oxygen therapeutic …

Simple Summary The association between hypoxia, cancer aggressiveness and decreased
therapeutic response is well-established. With a significant body of evidence suggesting that …

Objective: Oxygen-enhanced MRI (OE-MRI) or tissue oxygen-level dependent (TOLD) MRI
is an imaging technique under investigation for its ability to quantify and map oxygen …