The emergence of Zika virus and its new clinical syndromes

TC Pierson, MS Diamond - Nature, 2018 - nature.com
Zika virus (ZIKV) is a mosquito-transmitted flavivirus that has emerged as a global health
threat because of its potential to generate explosive epidemics and ability to cause …

Zika virus pathogenesis and tissue tropism

JJ Miner, MS Diamond - Cell host & microbe, 2017 - cell.com
Although Zika virus (ZIKV) was isolated approximately 70 years ago, few experimental
studies had been published prior to 2016. The recent spread of ZIKV to countries in the …

A human neutralizing antibody targets the receptor-binding site of SARS-CoV-2

R Shi, C Shan, X Duan, Z Chen, P Liu, J Song, T Song… - Nature, 2020 - nature.com
An outbreak of coronavirus disease 2019 (COVID-19),–, caused by severe acute respiratory
syndrome coronavirus 2 (SARS-CoV-2), has spread globally. Countermeasures are needed …

[HTML][HTML] Modified mRNA vaccines protect against Zika virus infection

JM Richner, S Himansu, KA Dowd, SL Butler, V Salazar… - Cell, 2017 - cell.com
The emergence of ZIKV infection has prompted a global effort to develop safe and effective
vaccines. We engineered a lipid nanoparticle (LNP) encapsulated modified mRNA vaccine …

Application of 3D bioprinting in the prevention and the therapy for human diseases

HG Yi, H Kim, J Kwon, YJ Choi, J Jang… - Signal Transduction and …, 2021 - nature.com
Rapid development of vaccines and therapeutics is necessary to tackle the emergence of
new pathogens and infectious diseases. To speed up the drug discovery process, the …

[HTML][HTML] Recurrent potent human neutralizing antibodies to Zika virus in Brazil and Mexico

DF Robbiani, L Bozzacco, JR Keeffe, R Khouri… - Cell, 2017 - cell.com
Antibodies to Zika virus (ZIKV) can be protective. To examine the antibody response in
individuals who develop high titers of anti-ZIKV antibodies, we screened cohorts in Brazil …

Passive immunotherapy of viral infections:'super-antibodies' enter the fray

LM Walker, DR Burton - Nature Reviews Immunology, 2018 - nature.com
Antibodies have been used for more than 100 years in the therapy of infectious diseases,
but a new generation of highly potent and/or broadly cross-reactive human monoclonal …

Immune response to dengue and Zika

A Elong Ngono, S Shresta - Annual review of immunology, 2018 - annualreviews.org
Flaviviruses such as dengue (DENV), yellow fever (YFV), West Nile (WNV), and Zika (ZIKV)
are human pathogens of global significance. In particular, DENV causes the most prevalent …

Animal models of Zika virus infection, pathogenesis, and immunity

TE Morrison, MS Diamond - Journal of virology, 2017 - Am Soc Microbiol
Zika virus (ZIKV) is an emerging mosquito-transmitted flavivirus that now causes epidemics
affecting millions of people on multiple continents. The virus has received global attention …

Current status of Zika virus vaccines: successes and challenges

A Pattnaik, BR Sahoo, AK Pattnaik - Vaccines, 2020 - mdpi.com
The recently emerged Zika virus (ZIKV) spread to the Americas, causing a spectrum of
congenital diseases including microcephaly in newborn and Guillain-Barré syndrome (GBS) …