Akt in cancer: Mediator and more
S Revathidevi, AK Munirajan - Seminars in cancer biology, 2019 - Elsevier
Akt is a serine/threonine kinase and it participates in the key role of the PI3K signaling
pathway. The Akt can be activated by a wide range of growth signals and the biochemical …
pathway. The Akt can be activated by a wide range of growth signals and the biochemical …
Genetic landscape and biomarkers of hepatocellular carcinoma
Hepatocellular carcinoma (HCC) has emerged as a major cause of cancer-related death. Its
mortality has increased in Western populations, with a minority of patients diagnosed at …
mortality has increased in Western populations, with a minority of patients diagnosed at …
Role of the microenvironment in the pathogenesis and treatment of hepatocellular carcinoma
V Hernandez–Gea, S Toffanin, SL Friedman, JM Llovet - Gastroenterology, 2013 - Elsevier
Hepatocellular carcinoma (HCC) is the most common primary liver tumor and the third
greatest cause of cancer-related death worldwide, and its incidence is increasing. Despite …
greatest cause of cancer-related death worldwide, and its incidence is increasing. Despite …
Pathogenic mechanisms in HBV-and HCV-associated hepatocellular carcinoma
A Arzumanyan, HM Reis, MA Feitelson - Nature Reviews Cancer, 2013 - nature.com
Hepatocellular carcinoma (HCC) is a highly lethal cancer, with increasing worldwide
incidence, that is mainly associated with chronic hepatitis B virus (HBV) and/or hepatitis C …
incidence, that is mainly associated with chronic hepatitis B virus (HBV) and/or hepatitis C …
The role of signaling pathways in the development and treatment of hepatocellular carcinoma
S Whittaker, R Marais, AX Zhu - Oncogene, 2010 - nature.com
Hepatocellular carcinoma (HCC) is a highly prevalent, treatment-resistant malignancy with a
multifaceted molecular pathogenesis. Current evidence indicates that during …
multifaceted molecular pathogenesis. Current evidence indicates that during …
Hepatocellular carcinoma pathogenesis: from genes to environment
PA Farazi, RA DePinho - Nature Reviews Cancer, 2006 - nature.com
Hepatocellular carcinoma is among the most lethal and prevalent cancers in the human
population. Despite its significance, there is only an elemental understanding of the …
population. Despite its significance, there is only an elemental understanding of the …
Combining crocin and sorafenib improves their tumor-inhibiting effects in a rat model of diethylnitrosamine-induced cirrhotic-hepatocellular carcinoma
Simple Summary Liver cancer represents one of the most lethal forms of cancer, with
hepatocellular carcinoma (HCC) accounting for the majority of its incidences and deaths …
hepatocellular carcinoma (HCC) accounting for the majority of its incidences and deaths …
Expression and function of the epidermal growth factor receptor in physiology and disease
J Chen, F Zeng, SJ Forrester, S Eguchi… - Physiological …, 2016 - journals.physiology.org
The epidermal growth factor receptor (EGFR) is the prototypical member of a family of
membrane-associated intrinsic tyrosine kinase receptors, the ErbB family. EGFR is activated …
membrane-associated intrinsic tyrosine kinase receptors, the ErbB family. EGFR is activated …
The inflammatory microenvironment in hepatocellular carcinoma: a pivotal role for tumor‐associated macrophages
D Capece, M Fischietti, D Verzella… - BioMed research …, 2013 - Wiley Online Library
Hepatocellular carcinoma (HCC) is one of the most common and aggressive human cancers
worldwide. HCC is an example of inflammation‐related cancer and represents a paradigm …
worldwide. HCC is an example of inflammation‐related cancer and represents a paradigm …
[PDF][PDF] Epidermal growth factor receptor inhibition attenuates liver fibrosis and development of hepatocellular carcinoma
Hepatocellular carcinoma (HCC) is the most rapidly increasing cause of cancer‐related
mortality in the United States. Because of the lack of viable treatment options for HCC …
mortality in the United States. Because of the lack of viable treatment options for HCC …