[HTML][HTML] Update on the genetics of systemic lupus erythematosus: genome-wide association studies and beyond
Systemic lupus erythematosus (SLE) is a chronic autoimmune disease of complex etiology
that primarily affects women of childbearing age. The development of SLE is attributed to the …
that primarily affects women of childbearing age. The development of SLE is attributed to the …
Recent advances in understanding the genetic basis of systemic lupus erythematosus
Systemic lupus erythematosus (SLE) is a polygenic chronic autoimmune disease leading to
multiple organ damage. A large heritability of up to 66% is estimated in SLE, with roughly …
multiple organ damage. A large heritability of up to 66% is estimated in SLE, with roughly …
[HTML][HTML] The representation of gender and race/ethnic groups in randomized clinical trials of individuals with systemic lupus erythematosus
T Falasinnu, Y Chaichian, MB Bass… - Current rheumatology …, 2018 - Springer
Abstract Purpose of Review This review evaluated gender and race/ethnic representation in
randomized controlled trials (RCTs) of patients with systemic lupus erythematosus (SLE) …
randomized controlled trials (RCTs) of patients with systemic lupus erythematosus (SLE) …
Renal involvement in lupus is characterized by unique DNA methylation changes in naïve CD4+ T cells
P Coit, P Renauer, MA Jeffries, JT Merrill… - Journal of …, 2015 - Elsevier
Systemic lupus erythematosus is a multi-system disease characterized by wide-spread DNA
methylation changes. To identify epigenetic susceptibility loci for lupus nephritis, genome …
methylation changes. To identify epigenetic susceptibility loci for lupus nephritis, genome …
[HTML][HTML] The autoimmune ecology
JM Anaya, C Ramirez-Santana, MA Alzate… - Frontiers in …, 2016 - frontiersin.org
Autoimmune diseases (ADs) represent a heterogeneous group of disorders that affect
specific target organs or multiple organ systems. These conditions share common …
specific target organs or multiple organ systems. These conditions share common …
An update on diet and nutritional factors in systemic lupus erythematosus management
M Aparicio-Soto, M Sánchez-Hidalgo… - Nutrition Research …, 2017 - cambridge.org
Systemic lupus erythematosus (SLE) is a chronic inflammatory and autoimmune disease
characterised by multiple organ involvement and a large number of complications. SLE …
characterised by multiple organ involvement and a large number of complications. SLE …
Epigenome-wide association study of peripheral blood mononuclear cells in systemic lupus erythematosus: identifying DNA methylation signatures associated with …
S Joseph, NI George, B Green-Knox, EL Treadwell… - Journal of …, 2019 - Elsevier
Systemic lupus erythematosus (SLE or lupus) is a heterogeneous autoimmune disease
characterized by the involvement of multiple organs and the production of antinuclear …
characterized by the involvement of multiple organs and the production of antinuclear …
[HTML][HTML] The role of microRNA-1246 in the regulation of B cell activation and the pathogenesis of systemic lupus erythematosus
S Luo, Y Liu, G Liang, M Zhao, H Wu, Y Liang, X Qiu… - Clinical …, 2015 - Springer
Background The pathogenesis of systemic lupus erythematosus (SLE) has not yet been
completely elucidated. One of the hallmarks of SLE is the production of autoantibodies by …
completely elucidated. One of the hallmarks of SLE is the production of autoantibodies by …
Immunoregulatory effects of indole-3-carbinol on monocyte-derived macrophages in systemic lupus erythematosus: A crucial role for aryl hydrocarbon receptor
Macrophages are versatile phagocytic cells in immune system with immunoregulatory
functions. However, the removal of apoptotic cells by macrophages is disturbed in systemic …
functions. However, the removal of apoptotic cells by macrophages is disturbed in systemic …
Environmental triggers in systemic lupus erythematosus
G Gulati, HI Brunner - Seminars in arthritis and rheumatism, 2018 - Elsevier
Systemic lupus erythematosus (SLE) is an autoimmune disease that can affect almost any
organ in the human body. Despite significant advancements in our understanding of SLE …
organ in the human body. Despite significant advancements in our understanding of SLE …