Matrigel, a basement-membrane matrix extracted from Engelbreth–Holm–Swarm mouse
sarcomas, has been used for more than four decades for a myriad of cell-culture …

Over the past 20 years, and particularly in the last decade, significant developmental
milestones have driven basic, translational, and clinical advances in the field of stem cell …

Recent advances in 3D culture technology allow embryonic and adult mammalian stem cells
to exhibit their remarkable self-organizing properties, and the resulting organoids reflect key …

Generation of pancreatic β cells from human pluripotent stem cells (hPSCs) holds promise
as a cell replacement therapy for diabetes. In this study, we establish a link between the …

The discovery of somatic cell nuclear transfer proved that somatic cells can carry the same
genetic code as the zygote, and that activating parts of this code are sufficient to reprogram …

Neural progenitor cell (NPC) culture within three-dimensional (3D) hydrogels is an attractive
strategy for expanding a therapeutically relevant number of stem cells. However, relatively …

Cell therapeutics hold tremendous regenerative potential and the therapeutic effect depends
on the effective delivery of cells. However, current cell delivery carriers with unsuitable …

Stem cells (SCs) hold great promise for cell therapy, tissue engineering, and regenerative
medicine as well as pharmaceutical and biotechnological applications. They have the …

Recent breakthroughs in pluripotent stem cell technologies have enabled a new class of in
vitro systems for functional modeling of human brain development. These advances, in …

Polymeric hydrogels are widely explored materials for biomedical applications. However,
they have inherent limitations like poor resistance to stimuli and low mechanical strength …