Green chemistry in organic synthesis: Recent update on green catalytic approaches in synthesis of 1, 2, 4-thiadiazoles

L Rubab, A Anum, SA Al-Hussain, A Irfan, S Ahmad… - Catalysts, 2022 - mdpi.com
Green (sustainable) chemistry provides a framework for chemists, pharmacists, medicinal
chemists and chemical engineers to design processes, protocols and synthetic …

Oxidative coupling with S–N bond formation

OM Mulina, AI Ilovaisky… - European Journal of …, 2018 - Wiley Online Library
Oxidative strategies are a powerful tool in organic synthesis for the formation of heteroatom–
heteroatom, carbon–heteroatom, and carbon–carbon bonds. Among these processes the …

Electrochemical Synthesis of 1, 2, 4‐Thiadiazoles through Intermolecular Dehydrogenative S‐N Coupling

JS Li, XY Xie, PP Yang, S Jiang, L Tao… - Advanced Synthesis …, 2020 - Wiley Online Library
An electrochemical intermolecular dehydrogenative coupling reaction of isothiocyanates
with 2‐aminopyridines/amidines was developed. Using n‐Bu4NI as the catalyst and …

One‐pot synthesis of quinazolines via elemental sulfur‐mediated oxidative condensation of nitriles and 2‐(Aminomethyl) anilines

Y Tan, W Jiang, P Ni, Y Fu… - Advanced Synthesis & …, 2022 - Wiley Online Library
A strategy for the synthesis of quinazolines via elemental sulfur‐mediated oxidative
condensation of nitriles and 2‐(aminomethyl) anilines was developed. The reaction was …

I2/TBHP promoted oxidative C–N bond formation at room temperature: Divergent access of 2-substituted benzimidazoles involving ring distortion

M Saha, AR Das - Tetrahedron Letters, 2018 - Elsevier
A new 'one pot'tandem synthesis of 2-substituted benzimidazoles has been developed from
2-aminobenzyl alcohol/2-aminobenzamide and different coupling partners (nitriles …

Isolation of unique heterocycles formed from pyridine-thiocarboxamides as diiodine, iodide, or polyiodide salts

AJ Peloquin, CD McMillen, WT Pennington - CrystEngComm, 2022 - pubs.rsc.org
Given their two reactive centers, thioamides serve as useful synthetic building blocks for
more complex heterocyclic molecules. The reaction of pyridine-4-thiocarboxamide (1) and …

Catalyst-free synthesis of α-thioacrylic acids via cascade thiolation and 1, 4-aryl migration of aryl alkynoates at room temperature

W Wei, L Wang, H Yue, YY Jiang… - Organic & Biomolecular …, 2018 - pubs.rsc.org
A simple and facile catalyst-free method for the construction of α-thioacrylic acids has been
developed from readily-available aryl alkynoates and thiols at room temperature. Various α …

Visible-light promoted serendipitous synthesis of 3,5-diaryl-1,2,4-thiadiazoles via oxidative dimerization of thiobenzamides

R Aggarwal, M Hooda - Journal of Sulfur Chemistry, 2022 - Taylor & Francis
In the present manuscript, we report serendipitous synthesis of 3, 5-diaryl-1, 2, 4-
thiadiazoles with the aid of a household compact fluorescent lamp (CFL). In presence of α …

One‐Pot Synthesis of 3‐Aryl‐5‐amino‐1,2,4‐thiadiazoles from Imidates and Thioureas by I2‐Mediated Oxidative Construction of the N–S Bond

L Chai, Z Lai, Q Xia, J Yuan, Q Bian… - European Journal of …, 2018 - Wiley Online Library
A simple and practical method for the one‐pot synthesis of 3‐aryl‐5‐amino‐1, 2, 4‐
thiadiazoles from imidates and thioureas has been developed. The protocol proceeds …

Recent advances in the synthesis of thiadiazoles

Y Xiao, S Sun, JT Yu, J Cheng - Synlett, 2019 - thieme-connect.com
Thiadiazole moieties are present in many natural products and pharmaceutical compounds
that possess a broad spectrum of biological activities, serving as antidepressant, anxiolytic …