Plasmids, a molecular cornerstone of antimicrobial resistance in the One Health era
Antimicrobial resistance (AMR) poses a substantial threat to human health. The widespread
prevalence of AMR is, in part, due to the horizontal transfer of antibiotic resistance genes …
prevalence of AMR is, in part, due to the horizontal transfer of antibiotic resistance genes …
[HTML][HTML] Antibiotic resistance in the environment
DG Larsson, CF Flach - Nature Reviews Microbiology, 2022 - nature.com
Antibiotic resistance is a global health challenge, involving the transfer of bacteria and
genes between humans, animals and the environment. Although multiple barriers restrict the …
genes between humans, animals and the environment. Although multiple barriers restrict the …
An omics-based framework for assessing the health risk of antimicrobial resistance genes
Antibiotic resistance genes (ARGs) are widespread among bacteria. However, not all ARGs
pose serious threats to public health, highlighting the importance of identifying those that are …
pose serious threats to public health, highlighting the importance of identifying those that are …
Examining horizontal gene transfer in microbial communities
IL Brito - Nature Reviews Microbiology, 2021 - nature.com
Bacteria acquire novel DNA through horizontal gene transfer (HGT), a process that enables
an organism to rapidly adapt to changing environmental conditions, provides a competitive …
an organism to rapidly adapt to changing environmental conditions, provides a competitive …
Antibiotic resistance genes from livestock waste: occurrence, dissemination, and treatment
Antibiotics are widely used in animal husbandry, and various types of antibiotic resistance
genes (ARGs) are frequently detected in livestock waste around the world. Conventional …
genes (ARGs) are frequently detected in livestock waste around the world. Conventional …
Antibiotic-resistance genes in waste water
Waste water and waste water treatment plants can act as reservoirs and environmental
suppliers of antibiotic resistance. They have also been proposed to be hotspots for …
suppliers of antibiotic resistance. They have also been proposed to be hotspots for …
Horizontal transfer of antibiotic resistance genes in the human gut microbiome
Highlights•The human gut microbiome harbours antibiotic resistance genes ('the
resistome').•Antibiotic resistance genes can spread in the gut microbiome through horizontal …
resistome').•Antibiotic resistance genes can spread in the gut microbiome through horizontal …
Uncultivated microbes in need of their own taxonomy
KT Konstantinidis, R Rosselló-Móra… - The ISME journal, 2017 - academic.oup.com
The great majority of microbial species remains uncultured, severely limiting their taxonomic
characterization and thus communication among scientists. Although Candidatus was …
characterization and thus communication among scientists. Although Candidatus was …
[HTML][HTML] Evolution of plasmid-mediated antibiotic resistance in the clinical context
A San Millan - Trends in microbiology, 2018 - cell.com
Antibiotic-resistant infections are an urgent problem in clinical settings because they sharply
increase mortality risk in critically ill patients. The horizontal spread of antibiotic resistance …
increase mortality risk in critically ill patients. The horizontal spread of antibiotic resistance …
Antibiotic resistance in wastewater treatment plants: Tackling the black box
Wastewater is among the most important reservoirs of antibiotic resistance in urban
environments. The abundance of carbon sources and other nutrients, a variety of possible …
environments. The abundance of carbon sources and other nutrients, a variety of possible …