Obesogens: How they are identified and molecular mechanisms underlying their action

N Mohajer, CY Du, C Checkcinco… - Frontiers in …, 2021 - frontiersin.org
Adult and childhood obesity have reached pandemic level proportions. The idea that caloric
excess and insufficient levels of physical activity leads to obesity is a commonly accepted …

A review of electrical impedance characterization of cells for label-free and real-time assays

HT Ngoc Le, J Kim, J Park, S Cho - BioChip Journal, 2019 - Springer
The aim of this review is to discuss label-free and real-time assays characterizing the
electrical impedance of cells for biomedical and pharmacological applications. Electrical …

Application of xCELLigence RTCA biosensor technology for revealing the profile and window of drug responsiveness in real time

D Kho, C MacDonald, R Johnson, CP Unsworth… - Biosensors, 2015 - mdpi.com
The xCELLigence technology is a real-time cellular biosensor, which measures the net
adhesion of cells to high-density gold electrode arrays printed on custom-designed E-plates …

Short-chain fatty acid acetate stimulates adipogenesis and mitochondrial biogenesis via GPR43 in brown adipocytes

J Hu, I Kyrou, BK Tan, GK Dimitriadis… - …, 2016 - academic.oup.com
Short-chain fatty acids play crucial roles in a range of physiological functions. However, the
effects of short-chain fatty acids on brown adipose tissue have not been fully investigated …

Vesicles shed by pathological murine adipocytes spread pathology: characterization and functional role of insulin resistant/hypertrophied adiposomes

T Camino, N Lago-Baameiro, SB Bravo… - International Journal of …, 2020 - mdpi.com
Extracellular vesicles (EVs) have recently emerged as a relevant way of cell to cell
communication, and its analysis has become an indirect approach to assess the cell/tissue …

Impedance-based cellular assays for regenerative medicine

W Gamal, H Wu, I Underwood, J Jia… - … of the Royal …, 2018 - royalsocietypublishing.org
Therapies based on regenerative techniques have the potential to radically improve
healthcare in the coming years. As a result, there is an emerging need for non-destructive …

Lack of adipocyte-fndc5/irisin expression and secretion reduces thermogenesis and enhances adipogenesis

D Pérez-Sotelo, A Roca-Rivada, I Baamonde… - Scientific reports, 2017 - nature.com
Irisin is a browning-stimulating molecule secreted from the fibronectin type III domain
containing 5 precursor (FNDC5) by muscle tissue upon exercise stimulation. Despite its …

Using real-time impedance-based assays to monitor the effects of fibroblast-derived media on the adhesion, proliferation, migration and invasion of colon cancer cells

CM Dowling, C Herranz Ors, PA Kiely - Bioscience reports, 2014 - portlandpress.com
Increasing our knowledge of the mechanisms regulating cell proliferation, migration and
invasion are central to understanding tumour progression and metastasis. The local tumour …

MicroRNA-146b-3p Promotes Cell Metastasis by Directly Targeting NF2 in Human Papillary Thyroid Cancer

C Yu, L Zhang, D Luo, F Yan, J Liu, S Shao, L Zhao… - Thyroid, 2018 - liebertpub.com
Background: MiR-146b has been reported to be overexpressed in papillary thyroid cancer
(PTC) tissues and associated with aggressive PTC. MiR-146b is regarded as a relevant …

Label-free biosensors in the field of stem cell biology

F Fathi, R Rahbarghazi, MR Rashidi - Biosensors and Bioelectronics, 2018 - Elsevier
A great body of evidence unveiled the existence of different stem cell types in various tissues
with efficient capability for self-renewal and differentiation. Characterization and …