A review of epigenetic changes in asthma: methylation and acetylation

M Sheikhpour, M Maleki, M Ebrahimi Vargoorani… - Clinical …, 2021 - Springer
Several studies show that childhood and adulthood asthma and its symptoms can be
modulated through epigenetic modifications. Epigenetic changes are inheritable …

A review on the pathophysiology of asthma remission

OA Carpaij, JK Burgess, HAM Kerstjens… - Pharmacology & …, 2019 - Elsevier
Asthma is a chronic respiratory condition, which is highly prevalent worldwide. Although no
cure is currently available, it is well recognized that some asthma patients can …

Cohort profile: the Isle of Wight whole population birth cohort (IOWBC)

SH Arshad, JW Holloway, W Karmaus… - International journal …, 2018 - academic.oup.com
By the late 1980s, it was clear that allergic diseases, including asthma, eczema, allergic
rhinitis and food allergy, had been increasing in recent decades, but the extent of this …

Changes in DNA methylation from pre-to post-adolescence are associated with pubertal exposures

L Han, H Zhang, A Kaushal, FI Rezwan, L Kadalayil… - Clinical …, 2019 - Springer
Background Adolescence is a period characterized by major biological development, which
may be associated with changes in DNA methylation (DNA-M). However, it is unknown to …

Multigenerational cohorts in patients with asthma and allergy

SH Arshad, W Karmaus, H Zhang… - Journal of Allergy and …, 2017 - Elsevier
Recent observations that disease risk can be transmitted across generations without the
need for direct exposure of the child to the index environmental insult has sparked interest in …

Association of season of birth with DNA methylation and allergic disease

GA Lockett, N Soto‐Ramírez, MA Ray, TM Everson… - Allergy, 2016 - Wiley Online Library
Background Season of birth influences allergy risk; however, the biological mechanisms
underlying this observation are unclear. The environment affects DNA methylation, with …

[HTML][HTML] Association between asthma and female sex hormones

RPC Baldaçara, I Silva - Sao Paulo Medical Journal, 2017 - SciELO Brasil
ABSTRACT CONTEXT AND OBJECTIVE: The relationship between sex hormones and
asthma has been evaluated in several studies. The aim of this review article was to …

The role of epigenetics in multi‐generational transmission of asthma: An NIAID workshop report‐based narrative review

LM Wheatley, JW Holloway, C Svanes… - Clinical & …, 2022 - Wiley Online Library
There is mounting evidence that environmental exposures can result in effects on health that
can be transmitted across generations, without the need for a direct exposure to the original …

Epigenetics of aging

MI Sierra, AF Fernández, MF Fraga - Current Genomics, 2015 - ingentaconnect.com
The best-known phenomenon exemplifying epigenetic drift (the alteration of epigenetic
patterns during aging) is the gradual decrease of global DNA methylation. Aging cells …

DNA methylation and allergic sensitizations: a genome‐scale longitudinal study during adolescence

H Zhang, A Kaushal, SK Merid, E Melén, G Pershagen… - Allergy, 2019 - Wiley Online Library
Background The presence of allergic sensitization has a major influence on the
development and course of common childhood conditions such as asthma and rhinitis. The …