Pathogenesis of allergic diseases and implications for therapeutic interventions

J Wang, Y Zhou, H Zhang, L Hu, J Liu, L Wang… - Signal transduction and …, 2023 - nature.com
Allergic diseases such as allergic rhinitis (AR), allergic asthma (AAS), atopic dermatitis (AD),
food allergy (FA), and eczema are systemic diseases caused by an impaired immune …

[HTML][HTML] Type 2 inflammation in asthma and other airway diseases

J Maspero, Y Adir, M Al-Ahmad… - ERJ open …, 2022 - Eur Respiratory Soc
Chronic inflammatory airway diseases, including asthma, chronic rhinosinusitis, eosinophilic
COPD and allergic rhinitis are a global health concern. Despite the coexistence of these …

[PDF][PDF] EPOS/EUFOREA update on indication and evaluation of Biologics in Chronic Rhinosinusitis with Nasal Polyps 2023

WJ Fokkens, AS Viskens, V Backer, D Conti… - Rhinology, 2023 - sioechcf.it
Severe chronic rhinosinusitis with nasal polyps (CRSwNP) is a debilitating disease with a
significant impact on the quality of life (QoL). It is typically characterized by a type 2 …

EUFOREA expert board meeting on uncontrolled severe chronic rhinosinusitis with nasal polyps (CRSwNP) and biologics: definitions and management

C Bachert, JK Han, M Wagenmann… - Journal of Allergy and …, 2021 - Elsevier
Uncontrolled severe chronic rhinosinusitis with nasal polyps (CRSwNP) is the most
bothersome phenotype of chronic rhinosinusitis; it is typically characterized by a type 2 …

Burden of disease in chronic rhinosinusitis with nasal polyps

C Bachert, N Bhattacharyya, M Desrosiers… - Journal of asthma and …, 2021 - Taylor & Francis
Chronic rhinosinusitis with nasal polyps (CRSwNP) is a predominantly type 2 inflammation-
mediated disease of the nasal mucosa and paranasal sinuses with an under-recognized …

Onset of effect and impact on health-related quality of life, exacerbation rate, lung function, and nasal polyposis symptoms for patients with severe eosinophilic asthma …

TW Harrison, P Chanez, F Menzella… - The lancet respiratory …, 2021 - thelancet.com
Background ANDHI was done to assess the efficacy of benralizumab, including onset of
effect and impact on health-related quality of life (HRQOL), exacerbation rate, lung function …

Role of IL‐25, IL‐33, and TSLP in triggering united airway diseases toward type 2 inflammation

H Hong, S Liao, F Chen, Q Yang, DY Wang - Allergy, 2020 - Wiley Online Library
Under the concept of" united airway diseases," the airway is a single organ wherein upper
and lower airway diseases are commonly comorbid. The upper and lower airways are lined …

[PDF][PDF] Executive summary of EPOS 2020 including integrated care pathways

WJ Fokkens, VJ Lund, C Hopkins, PW Hellings, R Kern… - Rhinology, 2020 - si.mahidol.ac.th
1.1. Summary The European Position Paper on Rhinosinusitis and Nasal Polyps 2020 is the
update of similar evidence based position papers published in 2005 and 2007 and 2012 (1 …

Advances and recent developments in asthma in 2020

L Cevhertas, I Ogulur, DJ Maurer, D Burla, M Ding… - Allergy, 2020 - Wiley Online Library
In this review, we discuss recent publications on asthma and review the studies that have
reported on the different aspects of the prevalence, risk factors and prevention, mechanisms …

[HTML][HTML] Chronic rhinosinusitis with nasal polyps: quality of life in the biologics era

J Mullol, A Azar, KM Buchheit, C Hopkins… - The Journal of Allergy …, 2022 - Elsevier
Chronic rhinosinusitis (CRS) affects up to 12% of the general population and is traditionally
divided into two main phenotypic subsets, based on the presence of nasal polyps …