[HTML][HTML] Functional biotransformation of phytoestrogens by gut microbiota with impact on cancer treatment

EK Farhat, EK Sher, A Džidić-Krivić, I Banjari… - The Journal of Nutritional …, 2023 - Elsevier
The human gut is a host for trillions of microorganisms, divided into more than 3,000
heterogeneous species that is called the gut microbiota. The gut microbiota composition can …

An updated review of soy-derived beverages: nutrition, processing, and bioactivity

R Olías, C Delgado-Andrade, M Padial… - Foods, 2023 - mdpi.com
The global market for plant-based drinks is experiencing rapid growth driven by consumer
demand for more sustainable diets, including vegetarian and vegan options. Soy beverages …

The G Protein-Coupled Estrogen Receptor (GPER): a critical therapeutic target for cancer

KA Hall, EJ Filardo - Cells, 2023 - mdpi.com
Estrogens have been implicated in the pathogenesis of various cancers, with increasing
concern regarding the overall rising incidence of disease and exposure to environmental …

Advances in the metabolic mechanism and functional characteristics of equol

Y Gong, J Lv, X Pang, S Zhang, G Zhang, L Liu… - Foods, 2023 - mdpi.com
Equol is the most potent soy isoflavone metabolite and is produced by specific intestinal
microorganisms of mammals. It has promising application possibilities for preventing chronic …

DNA methylation meningioma biomarkers: attributes and limitations

Z Li, Y Gao, J Zhang, L Han, H Zhao - Frontiers in Molecular …, 2023 - frontiersin.org
Meningioma, one of the most common primary central nervous system tumors, are classified
into three grades by the World Health Organization (WHO) based on histopathology. The …

In silico molecular docking and ADMET analysis for drug development of phytoestrogens compound with its evaluation of neurodegenerative diseases

FA Muslikh, RR Samudra, B Ma'arif… - Borneo Journal of …, 2022 - journal.umpr.ac.id
Neurodegenerative disease is one of the problems faced by postmenopausal women due to
estrogen deficiency. Phytoestrogen compounds can be used as an alternative treatment for …

Gut microbiome influences incidence and outcomes of breast cancer by regulating levels and activity of steroid hormones in women

SS Chapadgaonkar, SS Bajpai, MS Godbole - Cancer Reports, 2023 - Wiley Online Library
Background Breast cancer, the leading cancer type in women worldwide, is affected by
reproductive and nonreproductive factors. Estrogen and progesterone influence the …

Soy isoflavone-specific biotransformation product S-equol in the colon: Physiological functions, transformation mechanisms, and metabolic regulatory pathways

X Wang, B Chen, X Fang, Q Zhong, Z Liao… - Critical Reviews in …, 2024 - Taylor & Francis
Epidemiological data suggest that regular intake of soy isoflavones may reduce the
incidence of estrogen-dependent and aging-associated disorders. Equol is a metabolite of …

Gut microbiota-assisted synthesis, cellular interactions and synergistic perspectives of equol as a potent anticancer isoflavone

HS Tuli, A Kumar, K Sak, D Aggarwal, DS Gupta… - Pharmaceuticals, 2022 - mdpi.com
It is well known that, historically, plants have been an important resource of anticancer
agents, providing several clinically approved drugs. Numerous preclinical studies have …

Phytoestrogens and breast cancer: should French recommendations evolve?

A Mauny, S Faure, S Derbre - Cancers, 2022 - mdpi.com
Simple Summary Health agencies in several countries have different recommendations
regarding the consumption of soy isoflavones (phytoestrogens) in breast cancer (BC) …