Bacterial biofilms can cause medical problems and issues in technical systems. While a
large body of knowledge exists on the phenotypes of planktonic and of sessile cells in …

The intracellular signaling molecule cyclic di-GMP (c-di-GMP) regulates the lifestyle of
bacteria and controls many key functions and mechanisms. In the case of bacterial …

The opportunistic human pathogen Pseudomonas aeruginosa effectively colonizes host
epithelia using pili as primary adhesins. Here we uncover a surface-specific asymmetric …

The opportunistic pathogen Pseudomonas aeruginosa explores surfaces using twitching
motility powered by retractile extracellular filaments called type IV pili (T4P). Single cells …

The second messenger signaling molecule cyclic diguanylate monophosphate (c-di-GMP)
drives the transition between planktonic and biofilm growth in many bacterial species …

Bacteria thrive both in liquids and attached to surfaces. The concentration of bacteria on
surfaces is generally much higher than in the surrounding environment, offering bacteria …

Biofilm formation by Vibrio cholerae facilitates environmental persistence, and
hyperinfectivity within the host. Biofilm formation is regulated by 3', 5'-cyclic diguanylate (c-di …

Aggregating and forming biofilms on biotic or abiotic surfaces are ubiquitous bacterial
behaviors under various conditions. In clinical settings, persistent presence of biofilms …

Pseudomonas aeruginosa is an opportunistic human pathogen and is the primary cause of
nosocomial infections. Biofilm formation by this organism results in chronic and hard to …

Abstract Cyclic bis-(3', 5')-dimeric guanosine monophosphate (c-di-GMP) is ubiquitous in
many bacterial species, where it functions as a nucleotide-based secondary messenger and …