Less than a century ago, gastric cancer was the most common cancer in the United States
and perhaps throughout the world. Despite its worldwide decline in incidence over the past …

“Then Helen, Zeus' daughter, bethought her of another matter. She drugged the wine with an
herb that banishes all care, sorrow, and ill humor. Whoever drinks wine thus drugged cannot …

Objective The two major histological types of oesophageal cancer—adenocarcinoma (AC)
and squamous cell carcinoma (SCC)—are known to differ greatly in terms of risk factors and …

Background & Aims Northeast Iran has one of the highest reported rates of esophageal
squamous cell carcinoma (ESCC) worldwide. Decades of investigations in this region have …

Background Evidence is emerging for a role of opiates in various cancers. In this study, we
aimed to investigate the association between regular opium use and cancer incidence …

Background Gastric cancer (GC) is one of the most common cancers in Iran. Knowledge of
the epidemiology of the disease is essential in planning for prevention. So this study aimed …

An estimated 16· 5 million people worldwide illicitly use opiates, of whom 4 million use raw
opium. We did a systematic review to investigate the association between opium use and …

Objective Opioids are increasingly prescribed in the West and have deleterious GI
consequences. Pharmacological therapies to treat opioid-induced constipation (OIC) are …

Methods: Cases and controls were selected from patients who were referred to 4
endoscopic ultrasound centers in Tehran, Iran. We recruited 316 histopathologically (all …

Background: The International Agency for Research on Cancer (IARC) recently classified
opium use as a Group 1 carcinogen. However, much remains to be studied on the relation …