Reactive oxygen species (ROS), a class of highly bioactive molecules, have been widely
studied in various types of cancers. ROS are considered to be normal byproducts of …

Over the past few years, the cancer-related disease has had a high mortality rate and
incidence worldwide, despite clinical advances in cancer treatment. The drugs used for …

Most patients who die of cancer have disseminated disease that has become resistant to
multiple therapeutic modalities. Ample evidence suggests that the expression of ATP …

Cancer cells frequently display intrinsic or acquired resistance to chemically diverse
anticancer drugs, limiting therapeutic success. Among the main mechanisms of this …

It is generally accepted that recent advances in anticancer agents have contributed
significantly to the improvement of both the disease-free survival and quality of life in cancer …

Reactive oxygen species (ROS), a group of highly reactive ions and molecules, are
increasingly being appreciated as powerful signaling molecules involved in the regulation of …

Drug resistance is a daunting challenge in the treatment of breast cancer (BC). Exosomes,
as intercellular communicative vectors in the tumor microenvironment, play an important role …

Chemotherapy remains the standard of care for most cancers worldwide, however
development of chemoresistance due to the presence of the drug-effluxing ATP binding …

Peptide–drug conjugates (PDCs) represent an important class of therapeutic agents that
combine one or more drug molecules with a short peptide through a biodegradable linker …

P-glycoprotein (P-gp) is crucial in the active transport of various substrates with diverse
structures out of cells, resulting in poor intestinal permeation and limited bioavailability …