Multiple myeloma: a review of the epidemiologic literature

DD Alexander, PJ Mink, HO Adami… - … journal of cancer, 2007 - Wiley Online Library
Multiple myeloma, a neoplasm of plasma cells, accounts for∼∼ 15% of
lymphatohematopoietic cancers (LHC) and 2% of all cancers in the US. Incidence rates …

The interleukin 10− 819C/T polymorphism and cancer risk: a HuGE review and meta-analysis of 73 studies including 15,942 cases and 22,336 controls

Z Yu, Q Liu, C Huang, M Wu, G Li - Omics: a journal of integrative …, 2013 - liebertpub.com
The aim of the present work was to perform a meta-analysis to evaluate the association
between the interleukin 10 (IL-10)− 819C/T (rs1800871) polymorphism and cancer risk. A …

[HTML][HTML] Genetic polymorphisms of IL-6 promoter in cancer susceptibility and prognosis: a meta-analysis

X Peng, J Shi, W Sun, X Ruan, Y Guo, L Zhao, J Wang… - Oncotarget, 2018 - ncbi.nlm.nih.gov
IL-6 is critical for tumorigenesis. However, previous studies on the association of IL-6
promoter polymorphisms with predisposition to different cancer types are somewhat …

[HTML][HTML] Statistical meta-analysis to investigate the association between the Interleukin-6 (IL-6) gene polymorphisms and cancer risk

M Harun-Or-Roshid, MB Ali, Jesmin, MNH Mollah - PloS one, 2021 - journals.plos.org
A good number of genome-wide association studies (GWAS), including meta-analyses,
reported that single nucleotide polymorphisms (SNPs) of the IL-6 gene are significantly …

[HTML][HTML] Interleukin-6 receptor polymorphism is prevalent in HIV-negative Castleman disease and is associated with increased soluble interleukin-6 receptor levels

K Stone, E Woods, SM Szmania, OW Stephens… - PLoS …, 2013 - journals.plos.org
Multicentric Castleman Disease is largely driven by increased signaling in the pathway for
the plasma cell growth factor interleukin-6. We hypothesized that interleukin-6/interleukin-6 …

Associations of interleukin-6 gene polymorphisms with cancer risk: evidence based on 49,408 cancer cases and 61,790 controls

L Zhou, Y Zheng, T Tian, K Liu, M Wang, S Lin, Y Deng… - Gene, 2018 - Elsevier
Many molecular epidemiologic studies have shown that interleukin-6 (IL-6) polymorphisms
are significantly associated with susceptibility for various cancers. However, the conclusions …

[HTML][HTML] Circulating interleukin-6 and cancer: A meta-analysis using Mendelian randomization

G Tian, J Mi, X Wei, D Zhao, L Qiao, C Yang, X Li… - Scientific reports, 2015 - nature.com
Abstract Interleukin-6 (IL-6) plays a contributory role in the progression and severity of many
forms of cancer; it however remains unclear whether the relevance between circulating IL-6 …

Interleukin-6-related genotypes, body mass index, and risk of multiple myeloma and plasmacytoma

W Cozen, M Gebregziabher, DV Conti… - … Biomarkers & Prevention, 2006 - AACR
Abstract Interleukin-6 (IL-6) promotes normal plasma cell development and proliferation of
myeloma cells in culture. We evaluated IL-6 genotypes and body mass index (BMI) in a case …

[HTML][HTML] The Interleukin-10 Promoter Polymorphism rs1800872 (-592C>A), Contributes to Cancer Susceptibility: Meta-Analysis of 16 785 Cases and 19 713 Controls

Q Ding, Y Shi, B Fan, Z Fan, L Ding, F Li, W Tu, X Jin… - PLoS …, 2013 - journals.plos.org
Interleukin-10 (IL-10) is a multifunctional cytokine which participates in the development and
progression of various malignant tumors. To date, a number of case–control studies were …

Interleukin-1β and interleukin-6 gene polymorphisms are associated with manifestations of sickle cell anemia

P Vicari, SA Adegoke, DR Mazzotti… - Blood Cells, Molecules …, 2015 - Elsevier
Sickle cell anemia (SCA), a disorder characterized by both acute and chronic inflammation,
exhibits substantial phenotypic variability. Interleukin-1 beta (IL-1β) and IL-6 are important in …