Healthy aging and human longevity are intricate phenotypes affected by environmental
factors such as physical exercise, diet, health habits, and psychosocial situations as well as …

Accumulating research shows that prenatal exposure to maternal stress increases the risk
for behavioral and mental health problems later in life. This review systematically analyzes …

Extensive experimental animal studies and epidemiological observations have shown that
environmental influences during early development affect the risk of later pathophysiological …

Animal response to stressors such as harsh environmental conditions and demanding
biological processes requires energy generated through increased mitochondrial activity …

Telomere length shortens with age. Progressive shortening of telomeres leads to
senescence, apoptosis, or oncogenic transformation of somatic cells, affecting the health …

Nutritional conditions during key periods of development, when the architecture and modus
operandi of the body become established, are of profound importance in determining the …

Objective: To identify predictors of postnatal catch-up growth from birth to two years and its
relation to size and obesity at five years. Design: Regional prospective cohort study. Setting …

Small size at birth is linked with an increased risk of chronic diseases in later life. Poor
maternal nutrition during gestation may contribute to restricted fetal growth, leading to …

Diabetic nephropathy is the leading cause of chronic kidney disease (CKD) in western
countries. Notably, it has a rapidly rising prevalence in China. The patients, commonly …

Leukocyte telomere length (LTL) is a predictor of age-related disease onset and mortality.
The association in adults of psychosocial stress or stress biomarkers with LTL suggests …