Adipose tissue-derived components: From cells to tissue glue to treat dermal damage

L Vriend, B van der Lei, MC Harmsen, JA van Dongen - Bioengineering, 2023 - mdpi.com
In recent decades, adipose tissue transplantation has become an essential treatment
modality for tissue (volume) restoration and regeneration. The regenerative application of …

The molecular mechanisms of extracellular matrix-derived hydrogel therapy in idiopathic pulmonary fibrosis models

D Evangelista-Leite, ACO Carreira, MY Nishiyama… - Biomaterials, 2023 - Elsevier
Abstract Idiopathic Pulmonary Fibrosis (IPF) is a progressively debilitating lung condition
characterized by oxidative stress, cell phenotype shifts, and excessive extracellular matrix …

Arginine methylation and respiratory disease

B Zhang, Y Guan, D Zeng, R Wang - Translational Research, 2024 - Elsevier
Arginine methylation, a vital post-translational modification, plays a pivotal role in numerous
cellular functions such as signal transduction, DNA damage response and repair, regulation …

[HTML][HTML] Human adipose ECM alleviates radiation-induced skin fibrosis via endothelial cell-mediated M2 macrophage polarization

S Chinnapaka, KS Yang, Y Surucu, FB Bengur… - Iscience, 2023 - cell.com
Radiation therapy can lead to late radiation-induced skin fibrosis (RISF), causing movement
restriction, pain, and organ dysfunction. This study evaluated adipose-derived extracellular …

Lung dECM matrikine-based hydrogel reverses bleomycin-induced pulmonary fibrosis by suppressing M2 macrophage polarization

X Zhu, Y Yang, S Mao, Q Liu, Y Li, Y Yang, M Gao… - …, 2024 - iopscience.iop.org
Background: Recent studies have shown promising results using decellularized
extracellular matrix (dECM) matrikines-based hydrogel as attractive strategies for preventing …

Mice placental ECM components may provide a three-dimensional placental microenvironment

RSN Barreto, ACO Carreira, MD Silva, LA Fernandes… - Bioengineering, 2022 - mdpi.com
Bioethical limitations impair deeper studies in human placental physiology, then most
studies use human term placentas or murine models. To overcome these challenges, new …

Pulmonary matrix-derived hydrogels from patients with idiopathic pulmonary fibrosis induce a proinflammatory state in lung fibroblasts in vitro

JG Fernandez Davila, AK Singh, DW Moore… - Molecular Biology of …, 2024 - molbiolcell.org
Idiopathic pulmonary fibrosis (IPF), one of the most common forms of interstitial lung
disease, is a poorly understood, chronic, and often fatal fibroproliferative condition with only …

Investigating Extracellular Matrix-Derived Hydrogels From the Lungs of Patients With Idiopathic Pulmonary Fibrosis as an In Vitro Disease Model

JGF Davila - 2024 - search.proquest.com
Idiopathic pulmonary fibrosis (IPF), one of the most common forms of interstitial lung
disease, is a poorly understood, chronic, and often fatal condition with only two FDA …

Development and characterization of lung extracellular matrix-based models for respiratory research

A Ulldemolins Iglesias - 2024 - diposit.ub.edu
[eng] INTRODUCTION: The human respiratory system is responsible for the oxygen and
carbon dioxide exchange between the body and the external environment. It is composed of …

Advanced manufacturing: three-dimensional printing and bioprinting of models of lung and airways

S Tas, E Rehnberg, DE Wagner - 3D Lung Models for Regenerating Lung …, 2022 - Elsevier
Recent advances in materials science coupled with advanced manufacturing techniques
have opened up new possibilities for generating sophisticated models of lung and airways …