The membrane bilayer has a significant influence over the proteins embedded within it. G
protein-coupled receptors (GPCRs) form a large group of membrane proteins with a vast …

G-protein-coupled receptors (GPCRs) are of prime importance for cell signal transduction
mechanisms and are the target of many current and potential drugs. However, structural …

The presence and properties of serum autoantibodies against beta-adrenergic receptors in
patients with idiopathic dilated cardiomyopathy were studied using synthetic peptides …

Ethylene is the plant hormone that controls several features of plant growth and
development. The rate-limiting step in its synthesis is the formation of the ethylene precursor …

The mouse 5-HT2C receptor and its third and fourth (C-terminal) cytoplasmic domain have
been expressed as fusion proteins in bacteria. After purification antisera were generated …

Alkaline phosphatase fusions allow genes to be identified solely on the basis of their protein
products being exported from the cytoplasm. Thus, the use of such fusions helps render …

In Escherichia coli and other cell-based expression systems, there are critical difficulties in
synthesizing membrane proteins, such as the low protein expression levels and the …

Monoclonal antibodies that specifically recognize a membrane component located on the
sinusoidal domain of the hepatocyte have been used to screen a rat liver cDNA expression …

Structural studies of G protein-coupled receptors (GPCRs) gave insights into molecular
mechanisms of their action and contributed significantly to molecular pharmacology. This is …

Structure/function relationship of proteins belonging to the family of receptors coupled to
GTP-binding proteins Page 1 Eur. J. Biochem. 1-10 (1991) © FEBS 1991 0014295691001054 …