Mesenchymal stromal cells (MSCs) are currently being investigated for use in a wide variety
of clinical applications. For most of these applications, systemic delivery of the cells is …

Cardiovascular disease (CVD) is the leading cause of death worldwide. A search for more
effective treatments of CVD is increasingly needed. Major advances in nanotechnology …

The therapeutic efficacy of umbilical cord mesenchymal stem cells (UCMSCs) in acute
respiratory distress syndrome (ARDS) is mainly limited by the efficiency of homing of …

During the past decades, stem cell‐based therapy has acquired a promising role in
regenerative medicine. The application of novel cell therapeutics for the treatment of …

Stem cell therapy has emerged as a new strategy for treatment of ischemic heart disease.
Although umbilical cord-derived mesenchymal stromal cells (UC-MSCs) have been used …

Aims Atherosclerosis is a chronic inflammatory disease of the vasculature. Mesenchymal
stem cells (MSCs) exert immunomodulatory and immunosuppressive effects by secreting …

Cardiac muscle cells have an innate capacity to perceive and react to mechanical strain via
a mechanism known as mechanotransduction, whereby the cardiac muscle cells are …

Over the past two decades cardiac cell therapy (CCT) has emerged as a promising new
strategy to cure heart diseases at high unmet need. Thousands of patients have entered …

Cardiac matrix hydrogel has shown great promise as an injectable biomaterial due to the
possession of cardiac-specific extracellular matrix composition. A cardiac matrix hydrogel …

Background Insulin-like growth factor 1 (IGF-1) and hepatocyte growth factor (HGF) are
among the most promising growth factors for promoting cardiorepair. Here, we evaluated the …