Anatomo-functional origins of the cortical silent period: spotlight on the basal ganglia

D Zeugin, S Ionta - Brain sciences, 2021 - mdpi.com
The so-called cortical silent period (CSP) refers to the temporary interruption of
electromyographic signal from a muscle following a motor-evoked potential (MEP) triggered …

Amyloid-Induced Neurodegeneration: A Comprehensive Review through Aggregomics Perception of Proteins in Health and Pathology

S Bashir, A Aiman, M Shahid, AA Chaudhary… - Ageing Research …, 2024 - Elsevier
Amyloidosis of protein caused by fibrillation and aggregation are some of the most exciting
new edges not only in protein sciences but also in molecular medicines. The present review …

Cerebellar degeneration correlates with motor symptoms in Huntington disease

MK Singh‐Bains, NF Mehrabi, T Sehji… - Annals of …, 2019 - Wiley Online Library
Objective Huntington disease (HD) is an autosomal dominant neurodegenerative disorder
characterized by variable motor and behavioral symptoms attributed to major …

Beta-boswellic acid reverses 3-nitropropionic acid-induced molecular, mitochondrial, and histopathological defects in experimental rat model of Huntington's disease

TH Albekairi, A Kamra, S Bhardwaj, S Mehan, A Giri… - Biomedicines, 2022 - mdpi.com
Huntington's disease (HD) is distinguished by a triple repeat of CAG in exon 1, an increase
in poly Q in the Htt gene, and a loss of GABAergic medium spiny neurons (MSN) in the …

Apathy in Huntington's Disease: A review of the current conceptualization

M Camacho, RA Barker, SL Mason - 2018 - repository.cam.ac.uk
Apathy is one of the most common psychiatric symptoms experienced by patients with
Huntington's disease (HD). It appears early, progresses with the disease course and has …

Neuropathology and pathogenesis of extrapyramidal movement disorders: a critical update. II. Hyperkinetic disorders

KA Jellinger - Journal of Neural Transmission, 2019 - Springer
Extrapyramidal movement disorders comprise hypokinetic-rigid and hyperkinetic or mixed
forms, most of them originating from dysfunction of the basal ganglia (BG) and their …

Intellectual curiosity and action initiation are subtypes of apathy affected in Huntington disease gene expansion carriers

RK Hendel, MNN Hellem, LE Hjermind… - Cognitive and …, 2021 - journals.lww.com
Background: Apathy is a prevalent behavioral syndrome of Huntington disease (HD) that
can result in severe loss of function for the individual with HD and substantial caregiver …

Endophenotypical drift in Huntington's disease: a 5-year follow-up study

MNN Hellem, RK Hendel, T Vinther-Jensen… - Orphanet Journal of …, 2021 - Springer
Background Huntington's disease (HD) is clinically characterized by progressing motor,
cognitive and psychiatric symptoms presenting as varying phenotypes within these three …

Investigating altered limbic reward system in Huntington's Disease: Implications for apathy

V Bikou, I de Vicente, AE De Paepe, C Garcia-Gorro… - bioRxiv, 2024 - biorxiv.org
Huntington's disease (HD) is an inherited neurodegenerative condition characterized by
motor, cognitive, and behavioral impairments. Apathy, marked by reduced motivation and …

[PDF][PDF] Identification and characterisation of genetic variation that modifies age at onset in Huntington's disease

WB McAllister - 2019 - core.ac.uk
Huntington's disease (HD) is a progressive and ultimately fatal neurodegeneration caused
by a CAG repeat expansion in the huntingtin gene (HTT). The length of the CAG repeat is …