Update on the pathomechanism, diagnosis, and treatment options for rheumatoid arthritis
YJ Lin, M Anzaghe, S Schülke - Cells, 2020 - mdpi.com
Rheumatoid arthritis (RA) is an autoimmune disease that involves multiple joints bilaterally.
It is characterized by an inflammation of the tendon (tenosynovitis) resulting in both cartilage …
It is characterized by an inflammation of the tendon (tenosynovitis) resulting in both cartilage …
The role of oxidative stress in physiopathology and pharmacological treatment with pro‐and antioxidant properties in chronic diseases
A García-Sánchez, AG Miranda-Díaz… - Oxidative medicine …, 2020 - Wiley Online Library
Oxidative stress (OS) has the ability to damage different molecules and cellular structures,
altering the correct function of organs and systems. OS accumulates in the body by …
altering the correct function of organs and systems. OS accumulates in the body by …
Targeting immunometabolism as an anti-inflammatory strategy
EM Pålsson-McDermott, LAJ O'Neill - Cell research, 2020 - nature.com
The growing field of immunometabolism has taught us how metabolic cellular reactions and
processes not only provide a means to generate ATP and biosynthetic precursors, but are …
processes not only provide a means to generate ATP and biosynthetic precursors, but are …
Methotrexate an old drug with new tricks
Y Bedoui, X Guillot, J Sélambarom, P Guiraud… - International journal of …, 2019 - mdpi.com
Methotrexate (MTX) is the first line drug for the treatment of a number of rheumatic and non-
rheumatic disorders. It is currently used as an anchor disease, modifying anti-rheumatic drug …
rheumatic disorders. It is currently used as an anchor disease, modifying anti-rheumatic drug …
Strategies toward rheumatoid arthritis therapy; the old and the new
Currently, medications used to treat rheumatoid arthritis (RA) are glucocorticoids (GCs) and
nonsteroidal anti‐inflammatory drugs (NSAIDs), predominantly used for controlling the pain …
nonsteroidal anti‐inflammatory drugs (NSAIDs), predominantly used for controlling the pain …
[HTML][HTML] Methotrexate mechanism in treatment of rheumatoid arthritis
B Friedman, B Cronstein - Joint bone spine, 2019 - Elsevier
Methotrexate has been used in treatment of rheumatoid arthritis (RA) since the 1980s and to
this day is often the first line medication for RA treatment. In this review, we examine multiple …
this day is often the first line medication for RA treatment. In this review, we examine multiple …
[HTML][HTML] Anti-rheumatoid drugs advancements: New insights into the molecular treatment of rheumatoid arthritis
RB Mrid, N Bouchmaa, H Ainani, R El Fatimy… - Biomedicine & …, 2022 - Elsevier
Rheumatoid arthritis (RA) is one of more than 100 types of arthritis. This chronic autoimmune
disorder affects the lining of synovial joints in about 0.5% of people and may induce severe …
disorder affects the lining of synovial joints in about 0.5% of people and may induce severe …
Mechanism of action of methotrexate in rheumatoid arthritis, and the search for biomarkers
The treatment and outcomes of patients with rheumatoid arthritis (RA) have been
transformed over the past two decades. Low disease activity and remission are now …
transformed over the past two decades. Low disease activity and remission are now …
Anticancer properties of essential oils and other natural products
K Blowman, M Magalhães, MFL Lemos… - Evidence‐Based …, 2018 - Wiley Online Library
Essential oils are secondary metabolites with a key‐role in plants protection, consisting
primarily of terpenes with a volatile nature and a diverse array of chemical structures …
primarily of terpenes with a volatile nature and a diverse array of chemical structures …
[HTML][HTML] Redox regulation in metabolic programming and inflammation
HR Griffiths, D Gao, C Pararasa - Redox biology, 2017 - Elsevier
Energy metabolism and redox state are intrinsically linked. In order to mount an adequate
immune response, cells must have an adequate and rapidly available energy resource to …
immune response, cells must have an adequate and rapidly available energy resource to …