Pancreatic ductal adenocarcinoma (PDAC) is a leading cause of cancer-related mortality in
the Western world with limited therapeutic options and dismal long-term survival. The …

Abstract The 2020 Nobel Prize in Chemistry was awarded to Emmanuelle Charpentier and
Jennifer Doudna for the development of the Clustered regularly interspaced short …

Gallic acid (GA) is a phenolic molecule found naturally in a wide range of fruits as well as in
medicinal plants. It has many health benefits due to its antioxidant properties. This study …

MicroRNAs (miRNAs) are a class of posttranscriptional regulators that have recently
introduced an additional level of intricacy to our understanding of gene regulation. There are …

Hox genes, a highly conserved subgroup of the homeobox superfamily, have crucial roles in
development, regulating numerous processes including apoptosis, receptor signalling …

Nutrients can reverse or change epigenetic phenomena such as DNA methylation and
histone modifications, thereby modifying the expression of critical genes associated with …

MicroRNAs (miRNAs) are increasingly implicated in the regulation of metastasis. Despite
their potential as targets for anti-metastatic therapy, miRNAs have only been silenced in …

Objective Pancreatic cancer is characterised by invasive tumour spread and early
metastasis formation. During epithelial–mesenchymal transition, loss of the cell adhesion …

At the moment, pancreatic cancer is among the deadliest gastrointestinal diseases, and
pancreatic cancer growth is a complex biological process that is based on different kinds of …

The great majority of cancer deaths are due to metastasis, which remains a poorly
understood pathological process. The formation of a metastasis reflects a succession of …