Breast cancer: a molecularly heterogenous disease needing subtype-specific treatments
U Testa, G Castelli, E Pelosi - Medical Sciences, 2020 - mdpi.com
Breast cancer is the most commonly occurring cancer in women. There were over two-
million new cases in world in 2018. It is the second leading cause of death from cancer in …
million new cases in world in 2018. It is the second leading cause of death from cancer in …
Anticancer or carcinogenic? The role of estrogen receptor β in breast cancer progression
K Shen, H Yu, B Xie, Q Meng, C Dong, K Shen… - Pharmacology & …, 2023 - Elsevier
Estrogen receptor β (ERβ) is closely related to breast cancer (BC) progression. Traditional
concepts regard ERβ as a tumor suppressor. As studies show the carcinogenic effect of …
concepts regard ERβ as a tumor suppressor. As studies show the carcinogenic effect of …
CIBERSORT analysis of TCGA and METABRIC identifies subgroups with better outcomes in triple negative breast cancer
Studies have shown that the presence of tumor infiltrating lymphocytes (TILs) in Triple
Negative Breast Cancer (TNBC) is associated with better prognosis. However, the molecular …
Negative Breast Cancer (TNBC) is associated with better prognosis. However, the molecular …
Estrogen actions in triple-negative breast cancer
O Treeck, S Schüler-Toprak, O Ortmann - Cells, 2020 - mdpi.com
Triple-negative breast cancer (TNBC) lacks estrogen receptor (ER) α, but the expression of
estrogen receptors ERβ and G protein-coupled estrogen receptor 1 (GPER-1) is able to …
estrogen receptors ERβ and G protein-coupled estrogen receptor 1 (GPER-1) is able to …
[HTML][HTML] Cancer-associated fibroblasts secreted miR-103a-3p suppresses apoptosis and promotes cisplatin resistance in non-small cell lung cancer
H Wang, H Huang, L Wang, Y Liu, M Wang… - Aging (Albany …, 2021 - ncbi.nlm.nih.gov
Background: The cisplatin resistance of non-small cell lung cancer (NSCLC) patients results
in low response rate and overall survival rate. Exosomes contribute to pathological …
in low response rate and overall survival rate. Exosomes contribute to pathological …
The role of estrogen receptor beta in breast cancer
Y Zhou, X Liu - Biomarker research, 2020 - Springer
Breast cancer, a malignant tumor originating from mammary epithelial tissue, is the most
common cancer among women worldwide. Challenges facing the diagnosis and treatment …
common cancer among women worldwide. Challenges facing the diagnosis and treatment …
Estrogens and progestogens in triple negative breast cancer: do they harm?
M van Barele, BAM Heemskerk-Gerritsen, YV Louwers… - Cancers, 2021 - mdpi.com
Simple Summary Young women treated for breast cancer may experience early
menopause, which can negatively impact quality of life. The usual treatment for early …
menopause, which can negatively impact quality of life. The usual treatment for early …
[HTML][HTML] CRISPR/Cas9 based genome editing for targeted transcriptional control in triple-negative breast cancer
Breast cancer (BC) is the most common type of cancer in women at the global level and the
highest mortality rate has been observed with triple-negative breast cancer (TNBC) …
highest mortality rate has been observed with triple-negative breast cancer (TNBC) …
Estrogen receptor β4 regulates chemotherapy resistance and induces cancer stem cells in triple negative breast cancer
A Bano, JH Stevens, PS Modi, JÅ Gustafsson… - International Journal of …, 2023 - mdpi.com
Triple Negative Breast Cancer (TNBC) has the worst prognosis among all breast cancers,
and survival in patients with recurrence is rarely beyond 12 months due to acquired …
and survival in patients with recurrence is rarely beyond 12 months due to acquired …
The Potential of Hormonal Therapies for Treatment of Triple-Negative Breast Cancer
M Kirkby, AM Popatia, JR Lavoie, L Wang - Cancers, 2023 - mdpi.com
Simple Summary The presence of estrogen receptor beta, the androgen receptor, and the
glucocorticoid receptor on triple-negative breast cancer cells has opened the possibility for …
glucocorticoid receptor on triple-negative breast cancer cells has opened the possibility for …