Nanotechnology-based mRNA vaccines

S Chen, X Huang, Y Xue, E Álvarez-Benedicto… - Nature Reviews …, 2023 - nature.com
Abstract mRNA vaccines have emerged as a revolutionary tool to generate rapid and
precise immune responses against infectious diseases and cancers. Compared with …

mRNA vaccines in disease prevention and treatment

G Zhang, T Tang, Y Chen, X Huang… - Signal transduction and …, 2023 - nature.com
Abstract mRNA vaccines have emerged as highly effective strategies in the prophylaxis and
treatment of diseases, thanks largely although not totally to their extraordinary performance …

Estimated effectiveness of COVID-19 vaccines against Omicron or Delta symptomatic infection and severe outcomes

SA Buchan, H Chung, KA Brown, PC Austin… - JAMA network …, 2022 - jamanetwork.com
Importance The incidence of SARS-CoV-2 infection, including among individuals who have
received 2 doses of COVID-19 vaccine, increased substantially following the emergence of …

Effectiveness of a second BNT162b2 booster vaccine against hospitalization and death from COVID-19 in adults aged over 60 years

R Arbel, R Sergienko, M Friger, A Peretz… - Nature medicine, 2022 - nature.com
The rapid emergence of the B. 1.1. 529 (Omicron) variant of SARS-CoV-2 led to a global
resurgence of coronavirus disease 2019 (COVID-19). Israeli authorities approved a fourth …

SARS-CoV-2 vaccination and myocarditis in a Nordic cohort study of 23 million residents

Ø Karlstad, P Hovi, A Husby, T Härkänen… - JAMA …, 2022 - jamanetwork.com
Importance Reports of myocarditis after SARS-CoV-2 messenger RNA (mRNA) vaccination
have emerged. Objective To evaluate the risks of myocarditis and pericarditis following …

mRNA-1273 and BNT162b2 COVID-19 vaccines elicit antibodies with differences in Fc-mediated effector functions

P Kaplonek, D Cizmeci, S Fischinger… - Science translational …, 2022 - science.org
The successful development of several coronavirus disease 2019 (COVID-19) vaccines has
substantially reduced morbidity and mortality in regions of the world where the vaccines …

Lipid nanoparticles (LNPs) for in vivo RNA delivery and their breakthrough technology for future applications

M Jeong, Y Lee, J Park, H Jung, H Lee - Advanced drug delivery reviews, 2023 - Elsevier
RNA therapeutics show a significant breakthrough for the treatment of otherwise incurable
diseases and genetic disorders by regulating disease-related gene expression. The …

Effectiveness of the BNT162b2 vaccine after recovery from Covid-19

A Hammerman, R Sergienko, M Friger… - … England Journal of …, 2022 - Mass Medical Soc
Background The risk of infection with severe acute respiratory syndrome coronavirus 2
(SARS-CoV-2) decreases substantially among patients who have recovered from …

Characterization of the significant decline in humoral immune response six months post‐SARS‐CoV‐2 mRNA vaccination: a systematic review

KI Notarte, I Guerrero‐Arguero… - Journal of medical …, 2022 - Wiley Online Library
Accumulating evidence shows a progressive decline in the efficacy of coronavirus disease
2019 (COVID‐19)(severe acute respiratory syndrome coronavirus 2 [SARS‐CoV‐2]) …

Effectiveness of COVID-19 treatment with nirmatrelvir–ritonavir or molnupiravir among US veterans: target trial emulation studies with one-month and six-month …

KL Bajema, K Berry, E Streja, N Rajeevan… - Annals of internal …, 2023 - acpjournals.org
Background: Information about the effectiveness of oral antivirals in preventing short-and
long-term COVID-19–related outcomes in the setting of Omicron variant transmission and …