Two-photon calcium imaging of neuronal activity
In vivo two-photon calcium imaging (2PCI) is a technique used for recording neuronal
activity in the intact brain. It is based on the principle that, when neurons fire action …
activity in the intact brain. It is based on the principle that, when neurons fire action …
Imaging calcium in neurons
C Grienberger, A Konnerth - Neuron, 2012 - cell.com
Calcium ions generate versatile intracellular signals that control key functions in all types of
neurons. Imaging calcium in neurons is particularly important because calcium signals exert …
neurons. Imaging calcium in neurons is particularly important because calcium signals exert …
In vivo three-photon imaging of activity of GCaMP6-labeled neurons deep in intact mouse brain
High-resolution optical imaging is critical to understanding brain function. We demonstrate
that three-photon microscopy at 1,300-nm excitation enables functional imaging of …
that three-photon microscopy at 1,300-nm excitation enables functional imaging of …
[HTML][HTML] Dynamic reorganization of neuronal activity patterns in parietal cortex
Neuronal representations change as associations are learned between sensory stimuli and
behavioral actions. However, it is poorly understood whether representations for learned …
behavioral actions. However, it is poorly understood whether representations for learned …
A large field of view two-photon mesoscope with subcellular resolution for in vivo imaging
NJ Sofroniew, D Flickinger, J King, K Svoboda - elife, 2016 - elifesciences.org
Imaging is used to map activity across populations of neurons. Microscopes with cellular
resolution have small (< 1 millimeter) fields of view and cannot simultaneously image activity …
resolution have small (< 1 millimeter) fields of view and cannot simultaneously image activity …
Feedback-based wavefront shaping
IM Vellekoop - Optics express, 2015 - opg.optica.org
Light scattering was thought to be the fundamental limitation for the depth at which optical
imaging methods can retain their resolution and sensitivity. However, it was shown that light …
imaging methods can retain their resolution and sensitivity. However, it was shown that light …
Fluoro-and chromogenic chemodosimeters for heavy metal ion detection in solution and biospecimens
Heavy metal ions are of great concern, not only among the scientific community, especially
chemists, biologists, and environmentalists, but increasingly among the general population …
chemists, biologists, and environmentalists, but increasingly among the general population …
Advances in multiphoton microscopy technology
Multiphoton microscopy has enabled unprecedented dynamic exploration in living
organisms. A significant challenge in biological research is the dynamic imaging of features …
organisms. A significant challenge in biological research is the dynamic imaging of features …
Serial two-photon tomography for automated ex vivo mouse brain imaging
T Ragan, LR Kadiri, KU Venkataraju, K Bahlmann… - Nature …, 2012 - nature.com
Here we describe an automated method, named serial two-photon (STP) tomography, that
achieves high-throughput fluorescence imaging of mouse brains by integrating two-photon …
achieves high-throughput fluorescence imaging of mouse brains by integrating two-photon …
Simultaneous cellular-resolution optical perturbation and imaging of place cell firing fields
Linking neural microcircuit function to emergent properties of the mammalian brain requires
fine-scale manipulation and measurement of neural activity during behavior, where each …
fine-scale manipulation and measurement of neural activity during behavior, where each …