For the treatment and monitoring of Parkinson's disease (PD) to be scientific, a key
requirement is that measurement of disease stages and severity is quantitative, reliable, and …

Although levodopa remains the most efficacious symptomatic therapy for Parkinson disease
(PD), management of levodopa treatment during the advanced stages of the disease is …

Background Parkinson's disease (PD) is a neurodegenerative disorder whose diagnosis is
often challenging because symptoms may overlap with neurodegenerative parkinsonisms …

Objectives To use a data-driven approach to determine the existence and natural history of
subtypes of Parkinson's disease (PD) using two large independent cohorts of patients newly …

Parkinson's disease (PD) is associated with diverse clinical manifestations including motor
and non-motor signs and symptoms, and emerging biomarkers. We aimed to reveal the …

Parkinson's disease (PD) is a chronic disease that develops over years and varies
dramatically in its clinical manifestations. A preferred strategy to resolve this heterogeneity …

Background Our understanding of the etiology, pathophysiology, phenotypic diversity, and
progression of Parkinson's disease has stagnated. Consequently, patients do not receive …

Background Parkinson's disease is heterogeneous in symptom presentation and
progression. Increased understanding of both aspects can enable better patient …

Finding useful biomarkers for Parkinson’s disease | Science Translational Medicine news
careers commentary Journals Science Science brought to you byGoogle Indexer Log in science …

Objective We sought to identify motor features that would allow the delineation of individuals
with sleep study-confirmed idiopathic REM sleep behavior disorder (iRBD) from controls and …