Mantle-Cell Lymphoma Accounting for 5 to 7% of all lymphomas, mantle-cell lymphoma has
historically been associated with a poor outcome, but survival is improving. The …

Unprecedented advances in our understanding of the pathobiology, prognostication, and
therapeutic options in mantle cell lymphoma (MCL) have taken place in the last few years …

Abstract Background Ibrutinib, a Bruton's tyrosine kinase inhibitor, may have clinical benefit
when administered in combination with bendamustine and rituximab and followed by …

The field of mantle cell lymphoma (MCL) has witnessed remarkable progress due to
relentless advances in molecular pathogenesis, prognostication, and newer treatments …

PURPOSE Most patients with mantle cell lymphoma (MCL) are older. In this study, we
investigated the efficacy and safety of a chemotherapy-free combination with ibrutinib and …

Simple Summary Vincristine is a vinca alkaloid naturally occurring in Catharanthus roseus. It
belongs to antimitotic compounds, which arrest the cell cycle via disrupting microtubule …

PURPOSE In an update of the randomized, open-label, phase III European Mantle Cell
Lymphoma (MCL) Elderly trial (ClinicalTrials. gov identifier: NCT00209209), published in …

Mantle cell lymphoma (MCL) is clinically characterised by its heterogenous behaviour with
courses ranging from indolent cases that do not require therapy for years to highly …

Abstract Ubiquitin Proteasome System (UPS) is an adaptable and finely tuned system that
sustains proteostasis network under a large variety of physiopathological conditions. Its …

Due to genetic changes in DNA (deoxyribonucleic acid) sequences, cancer continues to be
the second most prevalent cause of death. The traditional target-directed approach, which is …