Microbiota in disease-transmitting vectors

J Wang, L Gao, S Aksoy - Nature Reviews Microbiology, 2023 - nature.com
Haematophagous arthropods, including mosquitoes, ticks, flies, triatomine bugs and lice
(here referred to as vectors), are involved in the transmission of various pathogens to …

Intrinsic factors driving mosquito vector competence and viral evolution: a review

J Lewis, EN Gallichotte, J Randall, A Glass… - Frontiers in Cellular …, 2023 - frontiersin.org
Mosquitoes are responsible for the transmission of numerous viruses of global health
significance. The term “vector competence” describes the intrinsic ability of an arthropod …

The role of mosquito hemocytes in viral infections

V Cardoso-Jaime, CV Tikhe, S Dong, G Dimopoulos - Viruses, 2022 - mdpi.com
Insect hemocytes are the only immune cells that can mount a humoral and cellular immune
response. Despite the critical involvement of hemocytes in immune responses against …

Immune reactions of vector insects to parasites and pathogens

NA Ratcliffe, CB Mello, HC Castro, P Dyson… - Microorganisms, 2024 - mdpi.com
This overview initially describes insect immune reactions and then brings together present
knowledge of the interactions of vector insects with their invading parasites and pathogens …

[HTML][HTML] Extracellular matrix proteins Pericardin and Lonely heart mediate periostial hemocyte aggregation in the mosquito Anopheles gambiae

CJ Meier, S Ahmed, JS Barr, TY Estévez-Lao… - Developmental & …, 2024 - Elsevier
An infection induces the migration of immune cells called hemocytes to the insect heart,
where they aggregate around heart valves called ostia and phagocytose pathogens in areas …

Mosquito pericardial cells upregulate Cecropin expression after an immune challenge

V Cardoso-Jaime, K Maya-Maldonado… - Developmental & …, 2023 - Elsevier
Most mosquito-transmitted pathogens grow or replicate in the midgut before invading the
salivary glands. Pathogens are exposed to several immunological factors along the way …

The effects of Gram-positive and Gram-negative bacterial toxins (LTA & LPS) on cardiac function in Drosophila melanogaster larvae

KE Brock, ER Elliott, MO Abul-Khoudoud… - Journal of Insect …, 2023 - Elsevier
The effects of Gram negative and positive bacterial sepsis depend on the type of toxins
released, such as lipopolysaccharides (LPS) or lipoteichoic acid (LTA). Previous studies …

Silencing Transglutaminase Genes TGase2 and TGase3 Has Infection-Dependent Effects on the Heart Rate of the Mosquito Anopheles gambiae

A Ramakrishnan, JF Hillyer - Insects, 2022 - mdpi.com
Simple Summary The immune and circulatory systems of insects are functionally integrated.
An infection induces the migration of immune cells called hemocytes to the surface of the …

Identification and functional studies of sand fly's immune-related genes

B Vomáčková Kykalová - 2024 - dspace.cuni.cz
Phlebotomine sand flies (Diptera, Psychodidae) from genera Phlebotomus and Lutzomyia
are proven vectors of Leishmania (Kinetoplastea, Trypanosomatida), causative agent of …