Amyotrophic lateral sclerosis-frontotemporal spectrum disorder (ALS-FTSD): Revised diagnostic criteria

MJ Strong, S Abrahams, LH Goldstein… - … lateral sclerosis and …, 2017 - Taylor & Francis
This article presents the revised consensus criteria for the diagnosis of frontotemporal
dysfunction in amyotrophic lateral sclerosis (ALS) based on an international research …

Progress and challenges in frontotemporal dementia research: a 20-year review

JR Hodges, O Piguet - Journal of Alzheimer's disease, 2018 - content.iospress.com
The landscape of frontotemporal dementia (FTD) has evolved remarkably in recent years
and is barely recognizable from two decades ago. Knowledge of the clinical …

Tackling clinical heterogeneity across the amyotrophic lateral sclerosis–frontotemporal dementia spectrum using a transdiagnostic approach

RM Ahmed, M Bocchetta, EG Todd, NY Tse… - Brain …, 2021 - academic.oup.com
The disease syndromes of amyotrophic lateral sclerosis (ALS) and frontotemporal dementia
(FTD) display considerable clinical, genetic and pathological overlap, yet mounting …

Apathy is associated with poor prognosis in amyotrophic lateral sclerosis

J Caga, MR Turner, S Hsieh, RM Ahmed… - European journal of …, 2016 - Wiley Online Library
Background and purpose Apathy is the most commonly reported behavioural change in
amyotrophic lateral sclerosis (ALS). However, the degree to which it affects prognosis and …

Behavioural changes predict poorer survival in amyotrophic lateral sclerosis

C Nguyen, J Caga, CJ Mahoney, MC Kiernan… - Brain and …, 2021 - Elsevier
Abstract Objective The Motor Neuron Disease Behavioural Scale (MiND-B) is a clinically
validated tool that was developed to detect behavioural dysfunction in patients with …

Primary lateral sclerosis and the amyotrophic lateral sclerosis–frontotemporal dementia spectrum

S Agarwal, E Highton-Williamson, J Caga… - Journal of …, 2018 - Springer
Aim To investigate whether primary lateral sclerosis (PLS) represents part of the
amyotrophic lateral sclerosis–frontotemporal dementia (ALS–FTD) spectrum of diseases …

Screening for cognitive and behavioral change in amyotrophic lateral sclerosis/motor neuron disease: a systematic review of validated screening methods

N Simon, LH Goldstein - Amyotrophic Lateral Sclerosis and …, 2019 - Taylor & Francis
Objectives: Cognitive and behavioral change in Amyotrophic Lateral Sclerosis (ALS) is well-
accepted. Several screening tools have been developed to detect such changes. Further …

Apathy is associated with parietal cortical-subcortical dysfunction in ALS

J Caga, S Tu, T Dharmadasa, YT Nga, MC Zoing… - Cortex, 2021 - Elsevier
Apathy is the core behavioural feature of frontotemporal dysfunction in amyotrophic lateral
sclerosis (ALS). Initiation and emotional manifestations of apathy significantly affect patients …

Apathy and its impact on patient outcome in amyotrophic lateral sclerosis

J Caga, S Hsieh, E Highton-Williamson, MC Zoing… - Journal of …, 2018 - Springer
Apathy is one of the most common behavioural symptoms of amyotrophic lateral sclerosis
(ALS), yet there are few studies that have investigated the relationship between apathy and …

Management and therapeutic perspectives in amyotrophic lateral sclerosis

S Mathis, P Couratier, A Julian, JM Vallat… - Expert Review of …, 2017 - Taylor & Francis
Introduction: Amyotrophic lateral sclerosis (ALS) is a fatal progressive neurodegenerative
disorder affecting both upper and lower motor neurons. Despite much research and effort …