Overview of the renin-angiotensin system in diabetic nephropathy

F Karimi, M Maleki, A Movahedpour… - Journal of the Renin …, 2024 - journals.sagepub.com
Diabetes mellitus is a multifactorial hyperglycemic condition characterized by biochemical,
molecular, and genetic variables, and leads to kidney dysfunction. Diabetic nephropathy …

Causal role of immune cells in diabetic nephropathy: a bidirectional Mendelian randomization study

SY Wang, Y Yu, XL Ge, S Pan - Frontiers in Endocrinology, 2024 - frontiersin.org
Background Diabetic nephropathy (DN) stands as a pervasive chronic renal disease
worldwide, emerging as the leading cause of renal failure in end-stage renal disease. Our …

Preclinical pharmacology and pharmacokinetics of curcumin tagged cilostazol nanodispersion for the management of diabetic nephropathy in wister rat model

A Rawat, S Chauhan, Monika, RP Singh, S Gupta… - In Silico …, 2024 - Springer
To evaluate the therapeutic potential of curcumin tagged cilostazol solid nano dispersion in
wistar rat streptozotocin-nicotinamide-induced diabetic nephropathy. Cilostazol (CLT), a …

Anti-apoptosis of podocytes and pro-apoptosis of mesangial cells for telmisartan in alleviating diabetic kidney injury

X Wei, Y Ma, Y Li, W Zhang, Y Zhong, Y Yu… - Frontiers in …, 2022 - frontiersin.org
Podocytes damage and mesangial cells expansion are two important pathological
manifestations of glomerular injury in early diabetes. Telmisartan, as an angiotensin type 1 …

A Bioequivalence Study of Azilsartan in Healthy Chinese Subjects

X Liu, X Dai, X Yu, H Zhou, J Xie - Clinical Pharmacology in …, 2024 - Wiley Online Library
Azilsartan is an angiotensin II receptor blocker used for treating adult hypertension. It
significantly improves cardiovascular outcomes in patients with high‐risk hypertension, heart …