Cationic liposomes (CLs) are effective carriers of a variety of therapeutics. Their applications
as vectors of nucleic acids (NAs), from long DNA and mRNA to short interfering RNA …

Motivated by the promises of gene therapy, there is great interest in developing non-viral
lipid-based vectors for therapeutic applications due to their low immunogenicity, low toxicity …

Cancer is an extremely complex disease, typically caused by mutations in cancer-critical
genes. By delivering therapeutic nucleic acids (NAs) to patients, gene therapy offers the …

Due to the potential use as transfecting agents of nucleic acids (DNA or RNA), multivalent
cationic non-viral vectors have received special attention in the last decade. Much effort has …

Over the last few years, DNA–surfactant complexes have gained traction as unique and
powerful materials for potential applications ranging from optoelectronics to biomedicine …

Cationic liposomes (CLs) are studied worldwide as carriers of DNA and short interfering
RNA (siRNA) for gene delivery and gene silencing, and related clinical trials are ongoing …

New pyridinium gemini amphiphiles having ethane-1, 2-dithiol spacer have been
synthesized by regioselective electrophilic cobromination of α-olefins. Ethane-1, 2-dithiol (1) …

The most important objective of the present study was to explain why cationic lipid (CL)-
mediated delivery of plasmid DNA (pDNA) is better than that of linear DNA in gene therapy …

Lipoplexes formed by the pEGFP-C3 plasmid DNA (pDNA) and lipid mixtures containing
cationic gemini surfactant of the 1, 2-bis (hexadecyl dimethyl ammonium) alkanes family …

The use of cationic lipids (CLs) as transfecting agents of DNA has received an increasing
attention in the last two decades. In order to improve the transfection efficiency with lower …