The interferon‐inducible protein with tetrapeptide repeats 3 (IFIT3) is one of the most
important members in both the IFIT family and interferon‐stimulated genes family. IFIT3 has …

Interferon-induced tetrapeptide repeat (IFIT) family proteins are an important component of
the antiviral immune response. There are four known members of the human IFIT family …

Abstract N6-methyladenosine (m6A) RNA methylation has recently been found involving in
regulatory mechanism of the tumor progression. Our aim was to explore the biological …

Cancer-associated fibroblasts (CAFs) are commonly acquired activated extracellular matrix
(ECM)-producing myofibroblasts, a phenotypes with multiple roles in hepatic fibrogenesis …

Abstract We introduce UniCell: Deconvolve Base (UCDBase), a pre-trained, interpretable,
deep learning model to deconvolve cell type fractions and predict cell identity across Spatial …

Background & Aims Remodeling the tumor microenvironment is a critical strategy for treating
advanced hepatocellular carcinoma (HCC). Yet, how distinct cell populations in the …

Background Colorectal cancer (CRC) is one of the most prevalent and deadly tumors
worldwide. The majority of CRC is resistant to anti-programmed cell death-1 (PD-1)-based …

Abstract Objectives Long non‐coding RNAs (lncRNAs) are key mediators in various
malignancies. Linc01503 was previously elucidated to promote gastric cancer (GC) cell …

Epigenetic regulation plays a critical role in the development, progression, and treatment of
tumors. The most common chemical modification of mRNA, called m6A, is essential for …

The type-I interferon (IFN) system represents the first line of defense against viral pathogens.
Recognition of the virus initiates complex signaling pathways that result in the transcriptional …