Unveil the secret of the bacteria and phage arms race
Bacteria have developed different mechanisms to defend against phages, such as
preventing phages from being adsorbed on the surface of host bacteria; through the …
preventing phages from being adsorbed on the surface of host bacteria; through the …
The dynamics of synthesis and localization of jumbo phage RNA polymerases inside infected cells
D Antonova, VV Belousova, E Zhivkoplias, M Sobinina… - Viruses, 2023 - mdpi.com
A nucleus-like structure composed of phage-encoded proteins and containing replicating
viral DNA is formed in Pseudomonas aeruginosa cells infected by jumbo bacteriophage …
viral DNA is formed in Pseudomonas aeruginosa cells infected by jumbo bacteriophage …
The action of Escherichia coli CRISPR–Cas system on lytic bacteriophages with different lifestyles and development strategies
A Strotskaya, E Savitskaya, A Metlitskaya… - Nucleic acids …, 2017 - academic.oup.com
CRISPR–Cas systems provide prokaryotes with adaptive defense against bacteriophage
infections. Given an enormous variety of strategies used by phages to overcome their hosts …
infections. Given an enormous variety of strategies used by phages to overcome their hosts …
From biophysics to 'omics and systems biology
Recent decades brought a revolution to biology, driven mainly by exponentially increasing
amounts of data coming from “'omics” sciences. To handle these data, bioinformatics often …
amounts of data coming from “'omics” sciences. To handle these data, bioinformatics often …
Molecular basis for lethal cross-talk between two unrelated bacterial transcription factors-the regulatory protein of a restriction-modification system and the repressor of …
A Wisniewska, E Wons, K Potrykus… - Nucleic Acids …, 2022 - academic.oup.com
Bacterial gene expression depends on the efficient functioning of global transcriptional
networks, however their interconnectivity and orchestration rely mainly on the action of …
networks, however their interconnectivity and orchestration rely mainly on the action of …
Endogenous Gene Regulation as a Predicted Main Function of Type IE CRISPR/Cas System in E. coli
CRISPR/Cas is an adaptive bacterial immune system, whose CRISPR array can actively
change in response to viral infections. However, Type IE CRISPR/Cas in E. coli (an …
change in response to viral infections. However, Type IE CRISPR/Cas in E. coli (an …
Regulator-dependent temporal dynamics of a restriction-modification system's gene expression upon entering new host cells: single-cell and population studies
Restriction-modification (RM) systems represent a first line of defense against invasive
DNAs, such as bacteriophage DNAs, and are widespread among bacteria and archaea. By …
DNAs, such as bacteriophage DNAs, and are widespread among bacteria and archaea. By …
Lethal perturbation of an Escherichia coli regulatory network is triggered by a restriction-modification system's regulator and can be mitigated by excision of the cryptic …
Bacterial gene regulatory networks orchestrate responses to environmental challenges.
Horizontal gene transfer can bring in genes with regulatory potential, such as new …
Horizontal gene transfer can bring in genes with regulatory potential, such as new …
Facile manipulation of protein localization in fission yeast through binding of GFP-binding protein to GFP
Y Chen, G Wang, H Hao, C Chao… - Journal of Cell …, 2017 - journals.biologists.com
ABSTRACT GFP-binding protein (or GBP) has been recently developed in various systems
and organisms as an efficient tool to purify GFP-fusion proteins. Due to the high affinity …
and organisms as an efficient tool to purify GFP-fusion proteins. Due to the high affinity …
Understanding key features of bacterial restriction-modification systems through quantitative modeling
Background Restriction-modification (RM) systems are rudimentary bacterial immune
systems. The main components include restriction enzyme (R), which cuts specific …
systems. The main components include restriction enzyme (R), which cuts specific …