The positive allosteric modulator BPAM344 and L‐glutamate introduce an active‐like structure of the ligand‐binding domain of GluK2
Y Bay, M Egeberg Jeppesen, K Frydenvang… - FEBS …, 2024 - Wiley Online Library
Kainate receptors belong to the family of ionotropic glutamate receptors and contribute to the
majority of fast excitatory neurotransmission. Consequently, they also play a role in brain …
majority of fast excitatory neurotransmission. Consequently, they also play a role in brain …
[HTML][HTML] Crystal structure of the GluK1 ligand-binding domain with kainate and the full-spanning positive allosteric modulator BPAM538
Y Bay, FJM Cabello, CC Koens, SM Frantsen… - Journal of Structural …, 2024 - Elsevier
Kainate receptors play an important role in the central nervous system by mediating
postsynaptic excitatory neurotransmission and modulating the release of the inhibitory …
postsynaptic excitatory neurotransmission and modulating the release of the inhibitory …