This review focuses on the effects of estrogens upon the cerebellum, a brain region long
ignored as a site of estrogen action. Highlighted are the diverse effects of estradiol within the …

Cerebral ischemia remains a leading cause of mortality worldwide. Although the incidence
of death has decreased over the years, surviving patients may suffer from long-term …

Stroke is one of the leading causes of death and disability worldwide. Experimental and
clinical studies showed that sex and age play an important role in deciding the outcome after …

Females who enter menopause prematurely via bilateral ovariectomy (surgical menopause)
have a significantly increased risk for cognitive decline and dementia. To help elucidate the …

The ovarian hormone 17β-estradiol (E2) exerts profound neuroprotective actions against
ischemia-induced brain damage in rodent models of global and focal ischemia. This review …

Surgically menopausal women incur a 2-to 5-fold increased risk for dementia and mortality
from neurological diseases, but the mechanisms underlying these increased risks remain …

Abstract 17β-Estradiol (E2), one of female sex hormones, has well-documented
neuroprotective effects in a variety of clinical and experimental disorders of the central …

Many studies have shown that estrogen replacement therapy (ERT) can improve cognitive
function and affect the structure of the brain, including the white matter, in postmenopausal …

Multiple sclerosis (MS) is a neurological disorder that causes disability and paralysis,
especially among young adults. Although interactions of several factors, such as viral …

Estrogens are neuroprotective factors for brain diseases, including hypertensive
encephalopathy. In particular, the hippocampus is highly damaged by high blood pressure …